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Multiplex-1 without added Iron

product on market Capsule Integrative Therapeutics Safety: 96/100
96/100

This product looks safe

  • Vitamin D: 10mg is 100.0× the Tolerable Upper Intake Level (0.1mg)
  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 595mg is 595.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
F Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains vitamins A, C, D, and E, which are supported by strong evidence for maintaining immune function and antioxidant defense. These nutrients play essential roles in cellular health and bone maintenance. The overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D: 10mg is 100.0× the Tolerable Upper Intake Level (0.1mg)

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 595mg is 595.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Multiplex-1 without added Iron
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
80
Servings
Other Combinations
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin A
3750 mcg (417% DV)
Vitamin C
450 mg (500% DV)
10 mg (50% DV)
Exceeds UL by 100.0× (UL: 0.1 mg) 608 studies (A:16, B:251)
134 mg (893% DV)
8.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
30 mg (2308% DV)
23.1× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
20 mg (1176% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
595 mcg DFE (149% DV)
Exceeds UL by 595.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
200 mcg (8333% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
200 mcg (667% DV)
6.7× RDA — above typical dose 27 studies (A:0, B:11)
45 mg (900% DV)
9.0× RDA — above typical dose 2 studies — no high-quality reviews
25 mg (5% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
Calcium
150 mg (12% DV)
150 mg (36% DV)
Within RDA (0.4× RDA) 316 studies (A:8, B:159)
12.5 mg (114% DV)
1.1× RDA — within safe limits 263 studies (A:6, B:134)
100 mcg (182% DV)
1.8× RDA — within safe limits 173 studies (A:0, B:67)
0.75 mcg (83% DV)
Market median: 2.0mg (138 products) 37 studies (A:0, B:11)
4 mg (174% DV)
1.7× RDA — within safe limits 9 studies — no high-quality reviews
50 mcg (111% DV)
1.1× RDA — within safe limits 3 studies — no high-quality reviews
NAC
25 mg
Market median: 600.0mg (7 products) 39 studies (A:2, B:13)
L-Glutathione
10 mg
750 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
50 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)

Other Ingredients

Gelatin Cellulose Ascorbyl Palmitate Silica Gelatin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Adults take 2 or 3 capsules twice daily with meals, or as recommended by a healthcare professional. Do not exceed recommended dose.

Warnings & Precautions

Warning: Do not take if you are pregnant or nursing. If you are taking prescription drugs, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Formulation Notes

Contains no wheat, gluten, dairy, or artificial colors, or flavors.

Daily Multivitamin

Additional Information

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

For more information, please visit integrativepro.com.

Quality Global Sourcing Bottled & Tested in the USA

Metadata

Product Details

UPC / SKU8 71791 00169 5
DSLD Entry Date2022-06-16
Product TypeOther Combinations
FormCapsule
BrandIntegrative Therapeutics
DSLD ID265920
Data Updated2026-04-11
Research

Research Evidence

566
Research Sources
56
Avg Quality
240
Meta Analysis
100
Clinical Trial
74
Systematic Review
71
Guideline
58
Rct
11
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
1
Observational
1
Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025 PubMed DOI
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024 PubMed DOI
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025 PubMed DOI
View all evidence for Iron →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.