Tyler Multiplex-1 With Iron

product on market Capsule Integrative Therapeutics 🟢 Safety: 99/100
Brand: Integrative Therapeutics
🟢 99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 63% of ingredients have research evidence
C Label Compliance Grade

Product Label

Label for Tyler Multiplex-1 With Iron
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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
80 Servings
Other Combinations Product Type
63% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin A
12500 IU (250% DV)
Vitamin C
450 mg (750% DV)
400 IU (100% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
200 IU (667% DV)
📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 134.0mg UL 1000mg
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
30 mg (1765% DV)
📊 23.1× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 30mg
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
45 mg (2250% DV)
📊 34.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 45mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
200 mcg (3333% DV)
📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.2mg
200 mcg (67% DV)
📊 6.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.2mg
100 mg (1000% DV)
📊 20.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 100mg
Calcium
150 mg (15% DV)
Iron
9 mg (50% DV)
150 mg (38% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 150mg
12 mg (80% DV)
✅ 1.1× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 12mg UL 40mg
100 mcg (143% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
750 mcg (38% DV)
✅ Within RDA (0.8× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.75mg UL 10mg
5 mg (250% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
100 mcg (83% DV)
✅ 2.9× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.1mg
50 mcg (67% DV)
✅ 1.1× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.05mg UL 2mg
25 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 25mg UL 3500mg
25 mg
📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)
This product: 25mg
L-Glutathione
10 mg
750 mcg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 0.75mg UL 20mg
50 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.05mg UL 1.8mg

Other Ingredients

Gelatin Potassium Bicarbonate Ascorbyl Palmitate Silicon Dioxide Soybean Oil soy flour

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (71% of products) Nutrient (61% of products) Approved Health (1% of products)

Target Groups

Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Recommendations: Take 2 or 3 capsules twice daily with meals, or as recommended by your healthcare practitioner.

⚠️ Warnings & Precautions

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or Poison Control Center immediately.

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

🧪 Formulation Notes

Contains no sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives.

Hypoallergenic vitamin-mineral multiple

Additional Information

A comprehensive, hypoallergenic supplement that combines multivitamin-mineral supplementation with enhanced antioxidant support. Formulated for maximum bioavailability with activated coenzyme forms of vitamins B2 and B6, flush-free inositol hexaniacinate, true GTF-chromium, and mineral citrates and malates.

This product contains natural ingredients; color variations are normal.

LI196007.C02 (B010128C)

EVIDENCE-BASED

Product Details

UPC / SKU 8 71791 00167 1
DSLD Entry Date 2013-07-25
Product Type Other Combinations
Form Capsule
Brand Integrative Therapeutics
DSLD ID 24190
Data Updated 2026-04-11

Research Evidence

566 Research Sources
56 Avg Quality Score
240 Meta Analysis
100 Clinical Trial
74 Systematic Review
71 Guideline
58 Rct
11 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
1 Observational
1 Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025
PubMed DOI
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019
PubMed DOI Cochrane
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022
PubMed DOI
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023
PubMed DOI
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024
PubMed DOI
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025
PubMed DOI
View all evidence for Iron →

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