Centrum Silver Adults 50+ by Centrum — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
74% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

Other Combinations Product Type

74% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

750 mcg (83% DV)

Vitamin C

60 mg (67% DV)

Vitamin D3

25 mcg (125% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

22.5 mg (150% DV)

✅ 1.5× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 22.5mg UL 1000mg

Vitamin K

30 mcg (25% DV)

✅ Within RDA (0.2× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.03mg

Thiamine

1.5 mg (125% DV)

✅ 1.2× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 1.5mg

Riboflavin

1.7 mg (131% DV)

✅ 1.3× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 1.7mg

Niacin

20 mg (125% DV)

✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

3 mg (176% DV)

✅ 2.3× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 3mg UL 100mg

Folate

667 mcg DFE (167% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 667mg UL 1.0mg

Vitamin B12

25 mcg (1042% DV)

📊 10.4× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.025mg

Biotin

30 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

10 mg (200% DV)

✅ 2.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 10mg

Calcium

220 mg (17% DV)

Phosphorus

20 mg (2% DV)

📊 Market median: 99.0mg (503 products) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 20mg UL 4000mg

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

50 mg (12% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 50mg

Zinc

11 mg (100% DV)

✅ Within RDA (1.0× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 11mg UL 40mg

Selenium

19 mcg (35% DV)

✅ Within RDA (0.3× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.019mg UL 0.4mg

Copper

0.5 mg (56% DV)

✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.5mg UL 10mg

Manganese

2.3 mg (100% DV)

✅ Within RDA (1.0× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2.3mg UL 11mg

Chromium

50 mcg (143% DV)

✅ 1.4× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.05mg

Molybdenum

45 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.045mg UL 2mg

Chloride

72 mg (3% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 72mg

Potassium

80 mg (2% DV)

Lutein

250 mcg

📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.25mg

Lycopene

300 mcg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 0.3mg

Other Ingredients

Calcium Carbonate Potassium Chloride Dibasic Calcium Phosphate Magnesium Oxide Microcrystalline Cellulose Ascorbic Acid DL-Alpha-Tocopheryl Acetate Maltodextrin Modified Corn Starch Corn Starch Contains Less Than 2% Of

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Adults: Take one (1) tablet daily with food. Not formulated for use in children. Do not exceed suggested use.

⚠️ Warnings & Precautions

Not formulated for use in children.

Do not exceed suggested use.

As with any supplement, if you are pregnant, nursing, or taking medication, consult your doctor before use.

If taking other supplements, read label, since supplements may contain the same ingredient.

Keep out of reach of children.

Bottle sealed with printed foil under cap. Do not use if foil is torn.

Not a replacement for cholesterol-lowering drugs

🧪 Formulation Notes

Verified non-GMO & gluten free

FloraGlo Lutein

B-vitamins and lycopene help promote heart health Zinc and B-vitamins help support normal brain function Vitamins A, C, and E and Lutein support healthy eyes

Additional Information

Heart health Brain health Eye health Whole body health

Store at room temperature. Keep bottle tightly closed.

This product is not intended to provide daily intake of lutein. Take with a diet rich in fruits and vegetables.

Non-GMO applies to Centrum & Centrum Silver Tablest only, learn more at centrum.com

Product Details

DSLD Entry Date 2019-07-24

Product Type Other Combinations

Form Tablet or Pill

Brand Centrum

DSLD ID 204705

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →