50 Plus One Daily by GNC Women's Ultra Mega — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
60% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Caplet(s) Serving Size

Other Combinations Product Type

60% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

3500 IU (70% DV)

Vitamin C

150 mg (250% DV)

Vitamin D

1200 IU (300% DV)

✅ 2.0× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.030000000000000002mg UL 0.1mg

Vitamin E

35 IU (117% DV)

✅ 1.6× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 23.450000000000003mg UL 1000mg

Vitamin K

60 mcg (75% DV)

✅ Within RDA (0.5× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.06mg

Thiamine

4.95 mg (330% DV)

📊 4.1× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 4.95mg

Riboflavin

3.74 mg (220% DV)

✅ 2.9× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 3.74mg

Niacin

22 mg (110% DV)

✅ 1.6× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 22mg UL 35mg

Vitamin B6

6.6 mg (330% DV)

📊 5.1× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 6.6mg UL 100mg

Folic Acid

600 mcg (150% DV)

✅ 1.5× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.6mg UL 1.0mg

Vitamin B12

110 mcg (1833% DV)

📊 45.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.11mg

Biotin

300 mcg (100% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

16.5 mg (165% DV)

📊 3.3× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 16.5mg

Calcium

500 mg (50% DV)

Iron

8 mg (44% DV)

Phosphorus

15 mg (2% DV)

📊 Market median: 99.0mg (503 products) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 15mg UL 4000mg

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

50 mg (13% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 50mg

Zinc

30 mg (200% DV)

✅ 2.7× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 30mg UL 40mg

Selenium

70 mcg (100% DV)

✅ 1.3× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.07mg UL 0.4mg

Copper

2 mg (100% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Manganese

2 mg (100% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Chromium

200 mcg (167% DV)

📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.2mg

Molybdenum

75 mcg (100% DV)

✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.075mg UL 2mg

Chloride

72 mg (2% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 72mg

Potassium

80 mg (2% DV)

Brain Health Blend:

Eye Health Support

Urinary Tract & Women's Health Blend:

Skin Structure & Antioxidant Support Blend:

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides Cool Mint Vanilla flavor Carmine color Sucralose

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Women ONLY

Product Information

📋 Directions for Use

One per day multivitamin

Directions: As a dietary supplement, take one caplet daily with food.

One per day

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Keep out of reach of children.

🧪 Formulation Notes

Women's Ultra Mega 50 Plus One Daily is a premium multivitamin providing 39 important nutrients essential for overall wellness, plus unique blends scientifically formulated to support the specific health needs of women, in one ultra concentrated pill.

Ultra concentrated with 39 important nutrients. Provides 18 vitamins & minerals at 100% daily value or more Strengthens bones with calcium and vitamin D-3 B vitamins to support energy production and metabolism

Additional Information

This product is endorsed by the GNC Medical Advisory Board. This team of esteemed physicians utilizes their extensive medical knowledge and experience to aid in the creation of GNC premium products, helping you to achieve optimal health through comprehensive nutritional support so you can live your best life!

Does your multivitamin compare? Ultra Concentrated Technology for Greater Benefits GNC Women's Ultra Mega 50 Plus One Daily Premium Multivitamin Leading Women's 50 Plus Multivitamin Nutrients delivered in one caplet 39 31 Nutrients with at least 100% daily value 18 9 At least 100% DV of 8 key B vitamins More vitamin B-12 important for Neurological Function and red blood cell formation. More vitamin C to support natural resistance 150 mg 120 mg Supports breast and colon health with more vitamin D 1200 IU 800 IU Customized women's health blends With Ginko, Phosphatidylserine, choline and inositol to support brain health Lutein for eye health support Cranberry for urinary tract support Supports healthy skin structure collagen and silica and protects against free radicals with Zeaxanthin

Physician Endorsed

CODE 179722 HOG

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Store in a cool, dry place.

Actual size

Scan & learn more

Compared to the leading women's 50 Plus multivitamin brand. Emerging research suggests that adequate daily vitamin D intake may play a role in supporting breast and colon health.

GNC Quality commitment For more than 78 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality ingredients and are manufactured under the strictest quality controls. GNC Guarantee If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you live well.

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Product Details

DSLD Entry Date 2017-01-25

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand GNC Women's Ultra Mega

DSLD ID 69784

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →