PhytoMatrix by Mannatech — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
53% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

2 Caplet(s) Serving Size

60 Servings

Botanical with Nutrients Product Type

53% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 {Calories}

Total Carbohydrates

1 Gram(s) (1% DV)

Vitamin A

2500 IU (50% DV)

Vitamin C

30 mg (50% DV)

Vitamin D

200 IU (50% DV)

✅ Within RDA (0.3× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.005mg UL 0.1mg

Vitamin E

15 IU (50% DV)

✅ Within RDA (0.7× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 10.05mg UL 1000mg

Thiamin

0.75 mg (50% DV)

✅ Within RDA (0.6× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 0.75mg

Riboflavin

0.8 mg (47% DV)

✅ Within RDA (0.6× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 0.8mg

Niacin

8 mg (40% DV)

✅ Within RDA (0.6× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 8mg UL 35mg

Vitamin B6

1 mg (50% DV)

✅ Within RDA (0.8× RDA of 1.3 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 1mg UL 100mg

Folic Acid

260 mcg (65% DV)

✅ Within RDA (0.7× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.26mg UL 1.0mg

Vitamin B12

3 mcg (50% DV)

✅ 1.3× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.003mg

Biotin

75 mcg (25% DV)

✅ 2.5× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.075mg

Pantothenic Acid

3 mg (30% DV)

✅ Within RDA (0.6× RDA of 5 mg) 📚 1 studies — no high-quality reviews

RDA 5mg This product: 3mg

Calcium

255 mg (26% DV)

Iron

3 mg (17% DV)

Iodine

75 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.075mg UL 1.1mg

Magnesium

5 mg (1% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 5mg

Zinc

7 mg (47% DV)

✅ Within RDA (0.6× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 7mg UL 40mg

Selenium

80 mcg (114% DV)

✅ 1.5× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.08mg UL 0.4mg

Copper

0.8 mg (40% DV)

✅ Within RDA (0.9× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.8mg UL 10mg

Manganese

1.2 mg (60% DV)

✅ Within RDA (0.5× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 1.2mg UL 11mg

Chromium

120 mcg (100% DV)

📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.12mg

Molybdenum

40 mcg (53% DV)

✅ Within RDA (0.9× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.04mg UL 2mg

Sodium

10 mg (1% DV)

Boron

400 mcg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 0.4mg UL 20mg

Vanadium

40 mcg

📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.04mg UL 1.8mg

Aloe Vera inner leaf gel powder

40 mg

📊 Market median: 100.0mg (166 products) 📚 10 studies (Tier A: 0, B: 1)

This product: 40mg

Broccoli concentrate

40 mg

Cranberry juice concentrate

40 mg

Grape skin extract

25 mg

Rutin

40 mg

📊 Market median: 500.0mg (19 products)

This product: 40mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Croscarmellose Sodium modified Starch Maltodextrin contains less than 2% of:

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommended Adult Use: Take 2 caplets two times daily with meals for optimal vitamin, mineral and phytonutrient support.

⚠️ Warnings & Precautions

WARNING: If you are pregnant, nursing, taking medication, have a health condition or are planning a medical procedure, consult your health professional before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Do not use if inner seal is missing or broken.

Keep out of reach of children.

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Contains Soy

🧪 Formulation Notes

No synthetic vitamins and minerals

Gluten-Free

Suitable for vegetarians

Contains Soy

Additional Information

The combination of vitamin A as mixed carotenoids and vitamin E as mixed tocopherols is known to increase their respective benefit.

Natural Vitamin C combined with other natural plant materials and phytochemicals has greater antioxidant effect than ascorbic acid alone.* Includes mixed tocopherols, the most beneficial form of vitamin E.

Patent Pending Formulation.

{plant}(TM)

Natural Vitamin Complex Plant-Sourced Minerals Standardized Phytochemicals

NSF(R)

Keep bottle tightly closed. Store in a cool, dry place.

Product Number 11201 US.11201.25.002

Supplement Facts Peel Here

PHYTOMATRIX

Standardized levels of plant-sourced minerals and stabilized phytochemicals, along with an all natural vitamin complex.

Product Details

DSLD Entry Date 2015-01-23

Product Type Botanical with Nutrients

Form Other (e.g. tea bag)

Brand Mannatech

DSLD ID 41093

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →