🟢 96/100

This product looks safe

  • Vitamin D: 40mg is 400.0× the Tolerable Upper Intake Level (0.1mg)
  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 65% of ingredients have research evidence
F Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin D: 40mg is 400.0× the Tolerable Upper Intake Level (0.1mg)
⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Light Green Caplet(s) Serving Size
30 Servings
Other Combinations Product Type
65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
1500 mcg RAE (167% DV)
Vitamin C
200 mg (222% DV)
40 mg (200% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 400.0× (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 40mg UL 0.1mg
20.1 mg (134% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20.1mg UL 1000mg
80 mcg (67% DV)
✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.08mg
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (3846% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (1000% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
10 mg (2% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
Calcium
500 mg (38% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
50 mg (12% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (364% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
2 mg (87% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (343% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
75 mcg (167% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
Super Antioxidant Blend
28.95 mg
Brain & Circulatory Support Blend
22.01 mg
Eye & Skin Health Complex
20.5 mg

Other Ingredients

Microcrystalline Cellulose Hydroxypropylmethylcellulose Maltodextrin Stearic Acid Cellulose Hydroxypropyl Cellulose Dicalcium Phosphate Sucrose Magnesium Stearate Titanium Dioxide Food Starch, Modified Mannitol Porcine Gelatin Fish Gelatin Polyethylene Glycol Corn Starch Calcium Silicate Talc Vanilla Mint Flavor, Natural DL-Alpha-Tocopherol Methylcellulose Glucose Syrup Chlorophyllin Stevia Leaf Extract Gum Arabic Vegetable Oil Sodium Ascorbate Mixed Carotenoids Magnesium Hydroxide Butylated Hydroxyanisole Butylated Hydroxytoluene Tricalcium Phosphate Anthocyanin Povidone Mixed Tocopherols Ascorbyl Palmitate Dextrin Medium Chain Triglyceride Starch, Modified Polyglycerol Fatty Acid Esters Sodium Aluminum Silicate Sodium Carboxymethylcellulose Sodium Chloride

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult Female (18 - 50 Years) Seniors/Mature (>50 Years) - Women ONLY

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take contents of one pack daily with food. For maximum benefits, take as directed every day.

⚠️ Warnings & Precautions

Warning: Cancer and Reproductive Harm – www.P65Warnings.ca.gov. Discontinue use two weeks prior to surgery. Do not exceed recommended intake. Inform your physician of this product's biotin content before any lab test. Niacin may cause a temporary flushing reaction.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition. Consult with your physician prior to use if you have high blood pressure or heart problems, or are taking prescription drugs.

Keep out of reach of children.

Contains: Soybeans, fish (anchovy, mackerel, sardine, smelt, whiting, pollock, salmon, tuna, cod or a combination thereof).

Contains a bioengineered food ingredient.

🧪 Formulation Notes

Our Quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you’re not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we’ll either refund your money or find a replacement product that is right for you. Life starts at 50 - your regimen starts here.

Specifically formulated for women 50 & older

With a multivitamin clinically proven to make you feel better, plus extra ingredients customized for women 50 and older, our Women's Vitapak Program 50 plus will help you support healthy aging. In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a basic multivitamin formula based upon multivariate statistical analyses of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid and vitamins B-6 and B-12) and key antioxidants and carotenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein and lycopene). Statistical improvements in SF-36 Vitality and Mental Health scores were also observed compared to placebo. Includes multivitamin + antioxidant formula + brain health complex + bone building complex + essential fatty acids

Additional Information

Store in a cool, dry place.

For more information: 1-888-462-2548

30 packs/30-day supply

Product Details

DSLD Entry Date 2025-05-21
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand GNC Women's
Bundle Vitapak Program 50 Plus
DSLD ID 331488
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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