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ProFema

product on market Tablet or Pill Pure Essence Safety: 99/100
99/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 57% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains vitamins A, C, E, and K2, which are supported by strong evidence for antioxidant protection and bone health. Vitashine is also included, though research evidence for its specific efficacy is more limited. The ingredient profile maintains a high safety score of 99/100.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for ProFema
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Tablet(s)
Serving Size
15
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1350 mcg (150% DV)
Vitamin C
1000 mg (1111% DV)
Vitashine
25 mcg (125% DV)
124.5 mg (830% DV)
8.3× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
50 mcg (42% DV)
Within RDA (0.4× RDA) 275 studies (A:9, B:175)
30 mg (2500% DV)
25.0× RDA — above typical dose 76 studies (A:0, B:33)
34 mg (2615% DV)
26.2× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
40 mg (2353% DV)
30.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
200 mcg (8333% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
100 mg (2000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
40 mg (7% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Calcium
200 mg (16% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
200 mg (47% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
150 mcg (273% DV)
2.7× RDA — within safe limits 173 studies (A:0, B:67)
1.5 mg (167% DV)
1.7× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
200 mcg (571% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
25 mcg (56% DV)
Within RDA (0.6× RDA) 3 studies — no high-quality reviews
Potassium
30 mg (2% DV)
Superfood Complex
908 mg
Herbal Extracts
700 mg
Co-Nutrients
440.3 mg
400 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Minerals
29 mg
Digestive Aids/Enzymes
27 mg

Other Ingredients

Silicon Dioxide Croscarmellose Sodium Stearic Acid Cellulose L-Leucine
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Four tablets once daily. May be taken with a meal or on an empty stomach. May be taken in divided doses.

Warnings & Precautions

Caution: Keep all supplements out of children's reach.

Not intended for use during pregnancy.

Formulation Notes

Non GMO Gluten Free

Vegan

Organic ingredients

Menopause multi Helps reduce hot flashes, mood swings

15,800 mg of whole food value

More than a multiple, ProFema is a complete nutritional system for women in their transitional years.

It provides perfect potencies of vitamins and minerals, an energy packed superfood complex, adaptogens and superior herbs, and specific menopausal support nutrients.

Supports: Immune function Bone health Healthy stress response Helps calm: Hot flashes Mood swings Associated menopausal discomfort

Does not contain: Wheat, milk, tree nuts, peanuts, soy, eggs, fish, shellfish

Additional Information

Vegan 100% Purity & Potency Guarantee 90 Day Money Back Guarantee

Please recycle

Made in USA

Storage: Keep closed in a cool, dry place.

Metadata

Product Details

UPC / SKU6 59670 00805 4
DSLD Entry Date2025-06-25
Product TypeOther Combinations
FormTablet or Pill
BrandPure Essence
DSLD ID327527
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.