🟢 99/100

This product looks safe

  • Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
  • 70% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size
120 Servings
Other Combinations Product Type
70% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
1050 mcg (117% DV)
Vitamin C
90 mg (100% DV)
25 mcg (125% DV)
✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.025mg UL 0.1mg
20.3 mg (135% DV)
✅ 1.4× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20.3mg UL 1000mg
60 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.06mg
1.2 mg (100% DV)
✅ Within RDA (1.0× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 1.2mg
1.3 mg (100% DV)
✅ Within RDA (1.0× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 1.3mg
16 mg (100% DV)
✅ 1.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 16mg UL 35mg
2 mg (118% DV)
✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 2mg UL 100mg
333 mcg DFE (83% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 333.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 333mg UL 1.0mg
6 mcg (250% DV)
✅ 2.5× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.006mg
40 mcg (133% DV)
✅ 1.3× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.04mg
15 mg (300% DV)
✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 15mg
Calcium
210 mg (16% DV)
Iron
8 mg (44% DV)
20 mg (2% DV)
📊 Market median: 99.0mg (503 products) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 20mg UL 4000mg
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
100 mg (24% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
11 mg (100% DV)
✅ Within RDA (1.0× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 11mg UL 40mg
100 mcg (182% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
0.9 mg (100% DV)
✅ Within RDA (1.0× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.9mg UL 10mg
2.3 mg (100% DV)
✅ Within RDA (1.0× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2.3mg UL 11mg
35 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.035 mg) 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.035mg
50 mcg (111% DV)
✅ 1.1× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.05mg UL 2mg
72 mg (3% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 72mg
Potassium
80 mg (2% DV)
600 mcg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 0.6mg

Other Ingredients

Starch Cellulose Stearic Acid FD&C Yellow #6 Citric Acid Croscarmellose Sodium Gelatin Magnesium Silicate Magnesium Stearate Maltodextrin Polyethylene Glycol Polyvinyl Alcohol Silicon Dioxide Titanium Dioxide

Label Claims — Verification

Nutrient
All Other
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult Male (18-50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, adults take one (1) tablet daily with any meal or as directed by your healthcare provider.

⚠️ Warnings & Precautions

Do not exceed recommended dosage. Individual results may vary. Stop use and contact a physician if adverse reactions occur. Do not use if product appears to be tampered with or seal is broken.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Keep out of reach of children.

Important information: Extended use of high levels of Vitamin A (excluding Beta-Carotene as the source) may increase the risk to adults of developing osteoporosis. Do not use this product if using other Vitamin A supplements.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product our of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

🧪 Formulation Notes

Gluten free

No added yeast or artificial flavors. Gluten free.

Men

Additional Information

Compare VS. Centrum Men

Store at room temperature.

Guaranteed Quality Laboratory Tested

Product Details

UPC / SKU 7 40985 22673 5
DSLD Entry Date 2025-01-23
Product Type Other Combinations
Form Tablet or Pill
Brand 21st Century
DSLD ID 326351
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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