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Ultra II Daily Sustained Release

product on market Tablet or Pill NaturesPlus Safety: 98/100
98/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 63% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins A, C, D3, E, and thiamine, which are supported by strong evidence for maintaining immune function and cellular health. These nutrients play critical roles in antioxidant defense and metabolic processes. The overall formulation maintains a high safety score, though evidence coverage for the specific blend is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Ultra II Daily Sustained Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
63%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
7500 mcg RAE (833% DV)
Vitamin C
100 mg (111% DV)
25 mcg (125% DV)
1.7× RDA — within safe limits 608 studies (A:16, B:251)
67 mg (447% DV)
4.5× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
100 mg (8333% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
100 mg (7692% DV)
76.9× RDA — above typical dose 13 studies (A:0, B:1)
100 mg NE (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5882% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
100 mcg (4167% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
100 mcg (333% DV)
3.3× RDA — above typical dose 27 studies (A:0, B:11)
100 mg (2000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
42 mg (8% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Calcium
40 mg (3% DV)
Iron
25 mg (139% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
20 mg (5% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
20 mg (182% DV)
1.8× RDA — within safe limits 263 studies (A:6, B:134)
10 mcg (18% DV)
Within RDA (0.2× RDA) 173 studies (A:0, B:67)
6.1 mg (265% DV)
2.7× RDA — within safe limits 9 studies — no high-quality reviews
15 mcg (43% DV)
Within RDA (0.4× RDA) 199 studies (A:1, B:55)
100 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
25 mg
Market median: 500.0mg (19 products)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Hesperidin Complex
5 mg

Other Ingredients

Potassium Gluconate Stearic Acid Ferrous Fumarate Microcrystalline Cellulose Dicalcium Phosphate Zinc Sulfate Manganese Gluconate Calcium Carbonate Hydroxypropyl Methylcellulose Magnesium Oxide Silica Magnesium Stearate Zinc Gluconate Rose Hips Potassium Amino Acid Complex Papaya isolated Soy Protein Ferrous Gluconate Bromelain Parsley Green Cabbage Watercress Acerola Cherry Icelandic Kelp Brown Rice Date Papaya Chlorella Spirulina Black Currant Garlic Apple Pectin Carrot Sunflower Seed Oil Broccoli Spinach Fig Beet Greens Lecithin Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: One tablet daily.

Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a physician or poison control center immediately.

Formulation Notes

Multi-Nutrient with Whole Foods

Overall Wellness

In a special base which provides for the gradual release of ingredients over a prolonged period of time. Micro-Gel sustained release system

Free from artificial colors and artificial preservatives.

Vegetarian

Additional Information

Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU0 97467 03042 8
DSLD Entry Date2023-12-14
Product TypeOther Combinations
FormTablet or Pill
BrandNaturesPlus
DSLD ID298775
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.