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Prenatal Advanced Care Vitamins & Minerals with 5-MTHF

product on market Capsule Kirkman Safety: 99/100
99/100

This product looks safe

  • Folate: 1530mg is 1530.0× the Tolerable Upper Intake Level (1.0mg)
  • 70% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains essential fat-soluble and antioxidant vitamins, including A, C, D3, E, and K1, which support immune function and cellular health. There is strong research evidence supporting the roles of these nutrients in prenatal wellness. The product maintains a high safety score of 99/100.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 1530mg is 1530.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Prenatal Advanced Care Vitamins & Minerals with 5-MTHF
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
70%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1500 mcg RAE (115% DV)
Vitamin C
250 mg (208% DV)
50 mcg (333% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
40 mg (212% DV)
2.7× RDA — within safe limits 179 studies (A:3, B:90)
40 mcg (44% DV)
Within RDA (0.3× RDA) 275 studies (A:9, B:175)
5 mg (357% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (313% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
20 mg NE (111% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
4 mg (200% DV)
3.1× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1530 mcg DFE (255% DV)
Exceeds UL by 1530.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
200 mcg (7143% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
30 mcg (86% DV)
Within RDA (1.0× RDA) 27 studies (A:0, B:11)
10 mg (143% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews
Calcium
200 mg (15% DV)
Iron
27 mg (100% DV)
150 mcg (52% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
20 mg (154% DV)
1.8× RDA — within safe limits 263 studies (A:6, B:134)
70 mcg (100% DV)
1.3× RDA — within safe limits 173 studies (A:0, B:67)
2 mg (154% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (77% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
100 mcg (222% DV)
2.9× RDA — within safe limits 199 studies (A:1, B:55)
75 mcg (150% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews

Other Ingredients

Hypromellose Water Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take two capsules daily or as directed by a physician.

Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of the reach of children. In case of overdose, call a doctor or poison control center immediately. Caution: Formulated for adults and children four years and older. For children under four, consult a physician.

Formulation Notes

Free of: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame

Hypoallergenic

Gluten-free

A complete prenatal vitamin for pregnant women

A complete prenatal vitamin for pregnant women

Additional Information

Important: Store in a cool dry place and tightly capped.

Ultra Tested cGMP

503.694.1600

Metadata

Product Details

UPC / SKU8 12325 02516 9
DSLD Entry Date2023-10-24
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
BrandKirkman
DSLD ID297243
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.