One Daily by Innate Response Formulas — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
65% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

90 Servings

Other Combinations Product Type

65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

180 mcg RAE (20% DV)

Vitamin C

60 mg (67% DV)

Vitamin D3

10 mcg (50% DV)

✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.01mg UL 0.1mg

Vitamin E

10 mg (67% DV)

✅ Within RDA (0.7× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 10mg UL 1000mg

Vitamin K

65 mcg (54% DV)

✅ Within RDA (0.5× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.065mg

Thiamine

5 mg (417% DV)

📊 4.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 5mg

Riboflavin

2 mg (154% DV)

✅ 1.5× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 2mg

Niacin

20 mg NE (125% DV)

✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

6 mg (353% DV)

📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 6mg UL 100mg

Folate

400 mcg DFE (100% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 400.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 400mg UL 1.0mg

Vitamin B12

15 mcg (625% DV)

📊 6.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.015mg

Biotin

30 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

10 mg (200% DV)

✅ 2.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 10mg

Iron

4.5 mg (25% DV)

Iodine

75 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.075mg UL 1.1mg

Zinc

6 mg (55% DV)

✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 6mg UL 40mg

Selenium

25 mcg (45% DV)

✅ Within RDA (0.5× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.025mg UL 0.4mg

Copper

0.1 mg (11% DV)

✅ Within RDA (0.1× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.1mg UL 10mg

Manganese

1.2 mg (52% DV)

✅ Within RDA (0.5× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 1.2mg UL 11mg

Chromium

40 mcg (114% DV)

✅ 1.1× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.04mg

Molybdenum

20 mcg (44% DV)

✅ Within RDA (0.4× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.02mg UL 2mg

Boron

500 mcg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 0.5mg UL 20mg

Fruit Phenolic Blend

10 mg

Other Ingredients

Cellulose Silica Stearic Acid

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Kosher Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: 1 tablet daily, or as directed by your healthcare practitioner. May be taken anytime throughout the day, even on an empty stomach.

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

🧪 Formulation Notes

Supports optimal health & well-being

Non GMO Dairy Free Soy free

Vegetarian

Kosher

In this INNATE Response product each vitamin or mineral is paired with an ideal whole food using our unique process to deliver guaranteed potency and the benefit of health-promoting compounds present in the whole food itself.

Additional Information

Please Recycle At INNATE Response we share your belief that nothing is more important than supporting your body's innate ability to heal. To that end, we develop nutrient-rich supplements.

To learn more about our seals, please visit innateresponse.com/standards.

Certified B Corporation Glyphosate Residue Free detoxproject.org Tested 125+ pesticides & herbicides Tested Gluten Free OK (Kosher)

See how they're made at innateresponse.com/showme. Learn more at: www.innateresponse.com

Product Details

UPC / SKU 0 51494 40002 9

DSLD Entry Date 2022-06-16

Product Type Other Combinations

Form Tablet or Pill

Brand Innate Response Formulas

DSLD ID 267820

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →