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MetaGlycemX

product on market Tablet or Pill Metagenics Safety: 97/100
97/100

This product looks safe

  • Niacin: 90mg is 2.6× the Tolerable Upper Intake Level (35mg)
  • Folate: 380mg is 380.0× the Tolerable Upper Intake Level (1.0mg)
  • 71% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins C, D, E, and B-complex, which support antioxidant defense and metabolic function. Research provides strong evidence for their roles in cellular health and energy production. The formulation maintains a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 90mg is 2.6× the Tolerable Upper Intake Level (35mg)

Folate: 380mg is 380.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for MetaGlycemX
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
300 mg (333% DV)
5 mcg (25% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
134 mg (893% DV)
8.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
15 mg (1250% DV)
12.5× RDA — above typical dose 76 studies (A:0, B:33)
9 mg (692% DV)
6.9× RDA — above typical dose 13 studies (A:0, B:1)
90 mg (563% DV)
Exceeds UL by 2.6× (UL: 35 mg) 196 studies (A:5, B:63)
9 mg (529% DV)
6.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
380 mcg DFE (170% DV)
Exceeds UL by 380.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
150 mcg (6250% DV)
62.5× RDA — above typical dose 139 studies (A:1, B:44)
2000 mcg (6667% DV)
66.7× RDA — above typical dose 27 studies (A:0, B:11)
30 mg (600% DV)
6.0× RDA — above typical dose 2 studies — no high-quality reviews
9 mg (82% DV)
Within RDA (0.8× RDA) 263 studies (A:6, B:134)
90 mcg (164% DV)
1.6× RDA — within safe limits 173 studies (A:0, B:67)
0.75 mg (83% DV)
Within RDA (0.8× RDA) 37 studies (A:0, B:11)
1.2 mg (52% DV)
Within RDA (0.5× RDA) 9 studies — no high-quality reviews
600 mcg (1714% DV)
17.1× RDA — above typical dose 199 studies (A:1, B:55)
Chinese Cinnamon (Cinnamomum cassia) bark powder
500 mg
300 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
L-Carnosine
50 mg

Other Ingredients

Microcrystalline Cellulose Cellulose Croscarmellose Sodium Silica Stearic Acid Calcium Silicate Magnesium Stearate Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two tablets once daily or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: If pregnant or nursing, or taking medications, consult your healthcare practitioner before use.

Keep out of the reach of children.

Formulation Notes

MetaGlycemX features a unique combination of green tea extract, cinnamon, and alpha-lipoic acid—nutrients that support healthy insulin metabolism when used as part of a healthy diet for maintaining healthy blood sugar levels already in the normal range. Green tea contains epigallocatechin gallate (EGCG), which may support healthy glucose metabolism. Alpha-lipoic acid is a potent antioxidant that acts as a free radical scavenger. MetaGlycemX also features other key supportive nutrients— including methylcobalamin, biotin, chromium, and vitamins C and E—combined in a well-rounded formula

This product is non-GMO and gluten-free.

Advanced nutritional support for healthy insulin & glucose metabolism

Practitioner exclusive

Additional Information

GF Certified Gluten-free

Metadata

Product Details

UPC / SKU7 55571 91204 6
DSLD Entry Date2022-05-19
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID265110
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.