Centrum Specialist Heart Multivitamin by Centrum — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
64% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

60 Servings

Other Combinations Product Type

64% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

525 mcg (58% DV)

Vitamin C

30 mg (33% DV)

Vitamin D3

5 mcg (25% DV)

✅ Within RDA (0.3× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.005mg UL 0.1mg

Vitamin E

6.8 mg (45% DV)

✅ Within RDA (0.5× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 6.8mg UL 1000mg

Vitamin K

12.5 mcg (10% DV)

✅ Within RDA (0.1× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.0125mg

Thiamine

0.8 mg (63% DV)

✅ Within RDA (0.7× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 0.8mg

Riboflavin

0.9 mg (65% DV)

✅ Within RDA (0.7× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 0.9mg

Niacin

10 mg (63% DV)

✅ Within RDA (0.7× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 10mg UL 35mg

Vitamin B6

2.5 mg (147% DV)

✅ 1.9× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2.5mg UL 100mg

Folate

333 mcg DFE (83% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 333.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 333mg UL 1.0mg

Vitamin B12

100 mcg (4167% DV)

📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.1mg

Biotin

15 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.015mg

Pantothenic Acid

5 mg (100% DV)

✅ Within RDA (1.0× RDA of 5 mg) 📚 1 studies — no high-quality reviews

RDA 5mg This product: 5mg

Calcium

54 mg (4% DV)

Iron

3 mg (17% DV)

Phosphorus

40 mg (3% DV)

✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 40mg UL 4000mg

Iodine

75 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.075mg UL 1.1mg

Magnesium

20 mg (5% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 20mg

Zinc

3.8 mg (34% DV)

✅ Within RDA (0.3× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 3.8mg UL 40mg

Selenium

10 mcg (18% DV)

✅ Within RDA (0.2× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.01mg UL 0.4mg

Copper

0.4 mg (44% DV)

✅ Within RDA (0.4× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.4mg UL 10mg

Manganese

1 mg (43% DV)

✅ Within RDA (0.4× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 1mg UL 11mg

Chromium

60 mcg (171% DV)

✅ 1.7× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.06mg

Molybdenum

38 mcg (83% DV)

✅ Within RDA (0.8× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.038mg UL 2mg

Chloride

29 mg (1% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 29mg

Sodium

5 mg (1% DV)

Potassium

32 mg (1% DV)

Phytosterols

400 mg

Other Ingredients

Phytosterols Microcrystalline Cellulose Dibasic Calcium Phosphate Croscarmellose Sodium Potassium Chloride Ascorbic Acid Magnesium Oxide Contains <2% of

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested Use: Adults: Take one (1) tablet twice daily with meals or snacks. Not formulated for use in children.

⚠️ Warnings & Precautions

Not formulated for use in children.

Contains: Soy.

As with any supplement, if you are taking medication consult your doctor before use.

Do not exceed suggested use.

Dietary supplementation with phytosterols is not suitable for pregnant or lactating women.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

If taking other supplements, read label, since supplements may contain the same ingredient.

Bottle sealed with printed foil under cap. Do not use if foil is torn.

🧪 Formulation Notes

Sitosterolemics: Contains phytosterols (sitosterols).

Made in Canada

High potency Super B complex with phytosterols

Targeted supports for heart health with the benefits of a complete multivitamin Supports healthy: Heart Blood pressure Circulation

Antioxidants, vitamins B6, B12, and folic acid to support heart health. Calcium & folic acid to help maintain blood pressure already within a normal range. Vitamins C & E to help support healthy blood vessel function.

Additional Information

Store at room temperature. Keep bottle tightly closed.

Questions? Comments? Call 1-877-CENTRUM (236-8786) For most recent product information, visit www.centrum.com New look!

Not a replacement for cholesterol-lowering drugs

Product Details

UPC / SKU 3 0005-4498-60 1

DSLD Entry Date 2021-12-18

Product Type Other Combinations

Form Tablet or Pill

Brand Centrum

DSLD ID 257004

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →