Multivitamin 50 Plus by GNC Women's — Ingredients, Evidence & Safety

🟢 97/100

This product looks safe

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
65% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Caplet(s) Serving Size

30 Servings

Other Combinations Product Type

65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1500 mcg (167% DV)

Vitamin C

200 mg (222% DV)

Vitamin D

40 mcg (200% DV)

✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.04mg UL 0.1mg

Vitamin E

20.1 mg (134% DV)

✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20.1mg UL 1000mg

Vitamin K

80 mcg (67% DV)

✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.08mg

Thiamine

50 mg (4167% DV)

📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 50mg

Riboflavin

50 mg (3846% DV)

📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 50mg

Niacin

50 mg (313% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 50mg UL 35mg

Vitamin B6

50 mg (2941% DV)

📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 50mg UL 100mg

Folate

680 mcg DFE (170% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 680mg UL 1.0mg

Vitamin B12

50 mcg (2083% DV)

📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.05mg

Biotin

300 mcg (1000% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

50 mg (1000% DV)

📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 50mg

Choline

10 mg (2% DV)

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 10mg UL 3500mg

Calcium

500 mg (38% DV)

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

50 mg (12% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 50mg

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Selenium

200 mcg (364% DV)

📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.2mg UL 0.4mg

Copper

2 mg (222% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Manganese

2 mg (87% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Chromium

120 mcg (343% DV)

📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.12mg

Molybdenum

75 mcg (167% DV)

✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.075mg UL 2mg

Super Antioxidant Blend

28.96 mg

Brain Support Blend

22.01 mg

Eye & Skin Health Complex

20.5 mg

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Stearic Acid Hydroxypropylcellulose Dicalcium Phosphate Magnesium Stearate Titanium Dioxide Polyethylene Glycol Talc natural Vanilla Mint flavor Chlorophyllin Stevia leaf extract

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Women ONLY Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take two caplets with food.

⚠️ Warnings & Precautions

Contains: Soybeans, fish (anchovy, mackerel, sardine, smelt, salmon, tuna, cod or a combination thereof).

Warning: Cancer and Reproductive Harm - www.P65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue two weeks prior to surgery. Inform your physician of this product's biotin content before any lab test. Niacin may cause a temporary flushing reaction.

Keep out of reach of children.

🧪 Formulation Notes

Conforms to USP <2091> for weight.

No artificial flavors, no wheat, gluten free, no dairy.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a leading multivitmin formula based upon multivariate statistical analysis of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid, and vitamins B-6 and B-12) key antioxidants and cartenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein, lycopene). Statistical improvements in SF-36 Vitality and Mental Health scores were also observed compared to placebo.

Bone health Features vitamin D plus calcium and magnesium for healthy bones Memory Support Includes choline to support memory function and ginkgo biloba for mental sharpness Skin health Includes hyaluronic acid for support skin repair Antioxidants Help protect against free radicals that can destroy healthy cells and promote the cell-aging process

Specially formulated for women 50 & older

Clinically proven to make you feel better Timed-Release

Additional Information

Store in a cool, dry place.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you are not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days, and we'll either refund your money or find a replacement product that is right for you.

Make 50 fabulous. Add this multivitamin to your regimen to help support your healthy lifestyle.

60-Day Supply

Product Details

DSLD Entry Date 2021-02-25

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand GNC Women's

DSLD ID 243737

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →