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50 Plus

product on market Other (e.g. tea bag) GNC Mega Men Safety: 97/100
97/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 65% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains a blend of fat-soluble and antioxidant vitamins that support immune function and bone health. There is strong clinical evidence for the roles of vitamins A, C, D, E, and K in maintaining cellular integrity and metabolic processes. The formulation maintains a high safety score for general use.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for 50 Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
30
Servings
Other Combinations
Product Type
65%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1500 mcg (167% DV)
Vitamin C
300 mg (333% DV)
40 mcg (200% DV)
2.7× RDA — within safe limits 608 studies (A:16, B:251)
20.1 mg (134% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
80 mcg (67% DV)
Within RDA (0.7× RDA) 275 studies (A:9, B:175)
50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
50 mcg (2083% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
10 mg (2% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
Calcium
200 mg (15% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (24% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
25 mg (227% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (364% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
120 mcg (343% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (167% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Prostate Health Blend
267.01 mg
Super Antioxidant Blend
28.96 mg
Brain Health Blend
21 mg

Other Ingredients

Microcrystalline Cellulose Cellulose Maltodextrin Hydroxypropyl Methylcellulose Hydroxypropylcellulose Dicalcium Phosphate Stearic Acid Magnesium Stearate Calcium Silicate natural Vanilla Mint flavor Stevia leaf extract Titanium Dioxide Caramel color Polyethylene Glycol Talc
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two caplets daily with food.

Warnings & Precautions

Warning: Cancer and Reproductive Harm - www.P65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Inform your physician of this product's biotin content before any lab test. Niacin may cause a temporary flushing reaction.

Keep out of reach of children.

Contains: Soybeans, fish (anchovy, mackerel, sardine, smelt, salmon, tuna, cod or a combination thereof).

Formulation Notes

Clinically studied multivitamin blend See carton for related information.

Timed-Release

Clinically studied

Additional Information

Store in a cool, dry place.

30-day supply

Metadata

Product Details

UPC / SKU0 48107 15501 8
DSLD Entry Date2020-08-23
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGNC Mega Men
DSLD ID228798
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.