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OsteoPrime

product on market Tablet or Pill Nature's Way Safety: 97/100
97/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 800mg is 800.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile includes Vitamin D and K, which have strong evidence for supporting bone health and calcium regulation. Vitamin C and thiamine provide essential antioxidant and metabolic support. Research for these combined ingredients is well-established, and the formulation maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 800mg is 800.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for OsteoPrime
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
100 mg (111% DV)
15 mcg (75% DV)
Within RDA (1.0× RDA) 608 studies (A:16, B:251)
300 mcg (250% DV)
2.5× RDA — within safe limits 275 studies (A:9, B:175)
20 mg (1667% DV)
16.7× RDA — above typical dose 76 studies (A:0, B:33)
20 mg (1538% DV)
15.4× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg DFE (200% DV)
Exceeds UL by 800.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
20 mcg (833% DV)
8.3× RDA — above typical dose 139 studies (A:1, B:44)
20 mg (400% DV)
4.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
600 mg (46% DV)
96 mg (8% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
250 mg (60% DV)
Within RDA (0.6× RDA) 316 studies (A:8, B:159)
20 mg (182% DV)
1.8× RDA — within safe limits 263 studies (A:6, B:134)
100 mcg (182% DV)
1.8× RDA — within safe limits 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
7 mg (304% DV)
3.0× RDA — within safe limits 9 studies — no high-quality reviews
50 mcg (111% DV)
1.1× RDA — within safe limits 3 studies — no high-quality reviews
20 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
1 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)

Other Ingredients

Cellulose Sodium Croscarmellose Stearic Acid Magnesium Stearate Hypromellose Glycerin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Adults take 4 tablets daily, during or after meals.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

Caution: If you are pregnant, nursing, or taking Coumadin (warfarin), or any medications, consult a healthcare professional before use.

Formulation Notes

Gluten free. No salt, yeast-derived ingredients, wheat, dairy products, or artificial flavors, or preservatives.

Bone health/density

Additional Information

Since 1969

Formulated by Jonathan Wright, M.D. and Alan Gaby, M.D.

Metadata

Product Details

UPC / SKU7 63948 07702 1
DSLD Entry Date2020-01-25
Product TypeOther Combinations
FormTablet or Pill
BrandNature's Way
DSLD ID212479
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.