🟢 99/100

This product looks safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • 68% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)

Label Data

3.3 Gram(s) Serving Size
90 Servings
Other Combinations Product Type
68% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
10000 IU (200% DV)
📊 3.3× RDA — above typical dose (UL: 3.0 mg) 📚 240 studies (Tier A: 5, B: 97)
RDA 0.9mg This product: 2.9999999999999996mg UL 3.0mg
Vitamin C
150 mg (250% DV)
1000 IU (250% DV)
✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.025mg UL 0.1mg
67 IU (223% DV)
✅ 3.0× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 44.89mg UL 1000mg
2.6 mg (173% DV)
✅ 2.2× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 2.6mg
3 mg (176% DV)
✅ 2.3× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 3mg
40 mg (200% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 40mg UL 35mg
4 mg (200% DV)
📊 3.1× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 4mg UL 100mg
216 mcg (54% DV)
✅ Within RDA (0.5× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.216mg UL 1.0mg
75 mcg (1250% DV)
📊 31.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.075mg
300 mcg (100% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
20 mg (200% DV)
📊 4.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 20mg
Calcium
53.8 mg (5% DV)
Iron
15 mg (83% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
25 mg (6% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 25mg
7.5 mg (50% DV)
✅ Within RDA (0.7× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 7.5mg UL 40mg
55 mcg (79% DV)
✅ Within RDA (1.0× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.055mg UL 0.4mg
100 mcg (5% DV)
✅ Within RDA (0.1× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.1mg UL 10mg
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (100% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
Potassium
110 mg (3% DV)
13.2 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 13.2mg

Other Ingredients

Fructose Citric Acid Mango flavor Orange flavor Malic Acid Passion Fruit flavor Rebaudioside A Maltodextrin Lo Han (fruit) extract natural Vanilla flavor

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (71% of products) Nutrient (61% of products) Approved Health (1% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions for use: Pour 1 level, white bottle capful of powder into the overcap. Add water to the line on the overcap (2 fl. oz./60 mL) and stir. As a dietary supplement, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.

⚠️ Warnings & Precautions

Note: If you are currently using any prescription drugs, have an ongoing medical condition, or if you are pregnant or breastfeeding, you should consult your healthcare provider before using this product.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Do not use if safety seal is broken or missing.

🧪 Formulation Notes

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6.

This vegetarian product contains no added wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.

This vegetarian product contains no added wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.

Additional Information

Supports a strong immune system Promotes normal cognitive performance Supplements dietary deficiencies Promotes skeletal, muscle and skin health The world's most advanced nutraceuticals

Store in a cool, dry place.

REV 1213

If barcode is missing or marked through, the sale of this product is not authorized or guaranteed by Market America.

Product Details

UPC / SKU 8 48570 00216 7
DSLD Entry Date 2019-05-28
Product Type Other Combinations
Form Powder
Brand Isotonix
DSLD ID 202669
Data Updated 2026-04-11

Research Evidence

566 Research Sources
56 Avg Quality Score
240 Meta Analysis
100 Clinical Trial
74 Systematic Review
71 Guideline
58 Rct
11 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
1 Observational
1 Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025
View all evidence for Iron →

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