Multivitamin Men's 50+ Advanced by up&up — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
72% of ingredients have research evidence

A Label Compliance Grade

Product Label

Label for Multivitamin Men's 50+ Advanced

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Label Data

1 Tablet(s) Serving Size

Other Combinations Product Type

72% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

2500 IU (50% DV)

Vitamin C

60 mg (100% DV)

Vitamin D

700 IU (175% DV)

✅ 1.2× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.0175mg UL 0.1mg

Vitamin E

22.5 IU (75% DV)

✅ Within RDA (1.0× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 15.075000000000001mg UL 1000mg

Vitamin K

20 mcg (25% DV)

✅ Within RDA (0.2× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.02mg

Thiamine

4.5 mg (300% DV)

📊 3.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 4.5mg

Riboflavin

3.4 mg (200% DV)

✅ 2.6× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 3.4mg

Niacin

20 mg (100% DV)

✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

6 mg (300% DV)

📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 6mg UL 100mg

Folic Acid

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

25 mcg (417% DV)

📊 10.4× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.025mg

Biotin

30 mcg (10% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

15 mg (150% DV)

✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 15mg

Calcium

120 mg (12% DV)

Iron

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

100 mg (25% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 100mg

Zinc

22.5 mg (150% DV)

✅ 2.0× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 22.5mg UL 40mg

Selenium

110 mcg (157% DV)

✅ 2.0× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.11mg UL 0.4mg

Copper

2 mg (100% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Manganese

4 mg (200% DV)

✅ 1.7× RDA — within safe limits 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 4mg UL 11mg

Chromium

180 mcg (150% DV)

📊 5.1× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.18mg

Molybdenum

90 mcg (120% DV)

✅ 2.0× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.09mg UL 2mg

Ginkgo extract

120 mg

📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)

This product: 120mg

Lycopene

300 mcg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 0.3mg

Other Ingredients

Calcium Carbonate Dicalcium Phosphate Magnesium Oxide Microcrystalline Cellulose Ginkgo Ascorbic Acid Croscarmellose Sodium Zinc Oxide DL-Alpha-Tocopheryl Acetate Niacinamide Polyvinyl Alcohol Calcium Pantothenate Stearic Acid Manganese Sulfate Crospovidone Titanium Dioxide Silicon Dioxide Polyethylene Glycol Pyridoxine Hydrochloride Talc Magnesium Stearate Thiamine Mononitrate Cupric Sulfate Riboflavin FD&C Blue #2 Aluminum Lake Vitamin A Acetate Chromium Chloride Folic Acid Lycopene Beta-Carotene Sodium Selenate Potassium Iodide Sodium Molybdate Biotin Cyanocobalamin Phytonadione Cholecalciferol

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Men ONLY Gluten Free

Product Information

📋 Directions for Use

Directions: Adults: Take one tablet daily, with food.

⚠️ Warnings & Precautions

Keep out of reach of children.

Do not use if printed seal under cap is broken or missing

Ask a doctor before use if you are taking ANY medication - especially any drug for anticoagulation (thinning the blood) including daily aspirin.

If you have a medical condition or bleeding problems or if you are planning any medical procedure, consult your doctor before using this product.

🧪 Formulation Notes

Does not contain iron

700 IU Vitamin D

GLUTEN FREE

A complete^ multivitamin with nutrients that matter to Men 50+ Men over 50 don't have to settle for an all-purpose multivitamin which may not meet their unique nutritional needs. This product is formulated specifically for both age and gender.

Additionally, it contains ginkgo to help promote memory and concentration.**

Additional Information

up&up(TM)

Complete^ multivitamin with nutrients that matter to Men 50+ to support: ~Memory and concentration with ginkgo** ~Heart health with Vitamins B6, B12, C, E and folic acid** ~Normal blood pressure* with Vitamin C, calcium, magnesium and Vitamin D** ~Eye health with Vitamins E, A, C and zinc** ~Immune health with Vitamins C, A, E and selenium** ~Energy metabolism with Vitamins B6, B12, pantothenic acid, folic acid and chromium**

^24 nutrients *Blood pressure levels already within the normal range

EXP 09/14 3AN1913

memory support**

SHOWN ACTUAL SIZE ABOVE

Store in a dry place at room temperature (59(0)-86(0)F).

094 02 0906

It provides important nutrients that support heart health, eye health and healthy blood pressure.* **

ID201455

Product Details

UPC / SKU 0 70030 62129 2

DSLD Entry Date 2013-05-24

Product Type Other Combinations

Form Tablet or Pill

Brand up&up

DSLD ID 20181

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →