🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 71% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Botanical with Nutrients Product Type
71% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
2500 IU (50% DV)
Vitamin C
60 mg (100% DV)
1000 IU (250% DV)
✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.025mg UL 0.1mg
22.5 IU (75% DV)
✅ Within RDA (1.0× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 15.075000000000001mg UL 1000mg
20 mcg (25% DV)
✅ Within RDA (0.2× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.02mg
4.5 mg (300% DV)
📊 3.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 4.5mg
3.4 mg (200% DV)
✅ 2.6× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 3.4mg
20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
6 mg (300% DV)
📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 6mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
25 mcg (417% DV)
📊 10.4× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.025mg
30 mcg (10% DV)
✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.03mg
15 mg (150% DV)
✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 15mg
Calcium
500 mg (50% DV)
Iron
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
50 mg (13% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
22.5 mg (150% DV)
✅ 2.0× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 22.5mg UL 40mg
20 mcg (29% DV)
✅ Within RDA (0.4× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.02mg UL 0.4mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
4 mg (200% DV)
✅ 1.7× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 4mg UL 11mg
180 mcg (150% DV)
📊 5.1× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.18mg
90 mcg (120% DV)
✅ 2.0× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.09mg UL 2mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 120mg

Other Ingredients

Calcium Carbonate Dicalcium Phosphate Ginkgo Magnesium Oxide Ascorbic Acid Microcrystalline Cellulose Croscarmellose Sodium Polyvinyl Alcohol Zinc Oxide Stearic Acid DL-Alpha-Tocopheryl Acetate Niacinamide Calcium Pantothenate Titanium Dioxide Polyethylene Glycol Manganese Sulfate Silicon Dioxide Talc Magnesium Stearate Crospovidone Pyridoxine Hydrochloride Thiamine Mononitrate Cupric Sulfate Riboflavin FD&C Yellow #6 Aluminum Lake Vitamin A Acetate Chromium Chloride FD&C Yellow #5 Aluminum Lake Folic Acid Beta-Carotene Potassium Iodide Sodium Molybdate Sodium Selenate FD&C Blue #2 Aluminum Lake Biotin Cholecalciferol Cyanocobalamin Phytonadione

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Women ONLY Gluten Free

Product Information

📋 Directions for Use

Directions: Adults: Take one tablet daily, with food.

⚠️ Warnings & Precautions

Caution: As a doctor before use if you are taking ANY medication - especially any drug for anticoagulation (thinning the blood) including daily aspirin.

If you have a medical condition or bleeding problems or if you are planning any medical procedure, consult your doctor before using this product.

If you are pregnant or nursing a baby, ask a doctor before using this product.

KEEP OUT OF REACH OF CHILDREN

Do not use if printed seal under cap is broken or missing.

🧪 Formulation Notes

GLUTEN FREE

women's 50+ advanced

1000 IU Vitamin D 500 mg calcium

Additional Information

Store in a dry place at room temperature (59(0)-86(0)F).

094 02 0907 : 2G271 UW F2

multivitamin/multimineral/herbal supplement

(image)(TM)

ID201455

Product Details

DSLD Entry Date 2012-08-24
Product Type Botanical with Nutrients
Form Tablet or Pill
Brand up&up
DSLD ID 12051
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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