🟢 97/100

This product looks safe

  • Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 75% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
1.05 mg (117% DV)
Vitamin C
250 mg (278% DV)
50 mcg (250% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
16.5 mg (110% DV)
✅ 1.1× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 16.5mg UL 1000mg
400 mcg (333% DV)
📊 3.3× RDA — above typical dose 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.4mg
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
12 mg (923% DV)
📊 9.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 12mg
80 mg (500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 80mg UL 35mg
20 mg (1176% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
667 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 667mg UL 1.0mg
600 mcg (25000% DV)
📊 250.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.6mg
500 mcg (1667% DV)
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg
45 mg (900% DV)
📊 9.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 45mg
Calcium
52 mg (4% DV)
75 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.075mg UL 1.1mg
20 mg (5% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 20mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (364% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
750 mcg (83% DV)
✅ Within RDA (0.8× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.75mg UL 10mg
3 mg (130% DV)
✅ 1.3× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 3mg UL 11mg
400 mcg (1143% DV)
📊 11.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.4mg
✅ 1.6× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 24mg UL 1000mg
Bororganic
2 mg
140 mcg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.14mg

Other Ingredients

Hypromellose Dicalcium Phosphate Calcium Laurate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: Take 2 capsules daily or as recommended by your health-care practitioner.

⚠️ Warnings & Precautions

Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

🧪 Formulation Notes

Foundational

Gluten free

This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic). This product uses Albion's TRAACS Calcium Bisglycinate Chelate, Chromium Nicotinate Glycinate Chelate, Copper Bisglycinate Chelate, Manganese Bisglycinate Chelate, Magnesium Bisglycinate Chelate, and Zinc Bisglycinate Chelate. This product uses Albion's Bororganic Boron Glycinate Complex.

Additional Information

Store tightly sealed in a cool, dry place.

Manufactured in the USA using US & imported ingredients NSF Contents Certified

Peel back for additional supplement facts Peel here Gamma tocopherol does not have a recognized IU equivalent.

Product Details

UPC / SKU 6 93749 00684 8
DSLD Entry Date 2025-04-24
Product Type Other Combinations
Form Capsule
Brand Thorne
DSLD ID 328819
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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