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OsteoPrime

product on market Capsule Nature's Way Safety: 97/100
97/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 800mg is 800.0× the Tolerable Upper Intake Level (1.0mg)
  • 58% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin D3 and K provide strong evidence for supporting bone health and calcium regulation, while Vitamin C and thiamine contribute to general cellular function. However, the overall evidence coverage for this specific ingredient profile is limited. The formulation maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 800mg is 800.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for OsteoPrime
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
58%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
100 mg (111% DV)
15 mcg (75% DV)
Within RDA (1.0× RDA) 608 studies (A:16, B:251)
300 mcg (250% DV)
2.5× RDA — within safe limits 275 studies (A:9, B:175)
20 mg (1667% DV)
16.7× RDA — above typical dose 76 studies (A:0, B:33)
20 mg (1538% DV)
15.4× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg DFE (200% DV)
Exceeds UL by 800.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
20 mcg (833% DV)
8.3× RDA — above typical dose 139 studies (A:1, B:44)
20 mg (400% DV)
4.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
600 mg (46% DV)
96 mg (8% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
250 mg (60% DV)
Within RDA (0.6× RDA) 316 studies (A:8, B:159)
20 mg (182% DV)
1.8× RDA — within safe limits 263 studies (A:6, B:134)
100 mcg (182% DV)
1.8× RDA — within safe limits 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
7 mg (304% DV)
3.0× RDA — within safe limits 9 studies — no high-quality reviews
50 mcg (111% DV)
1.1× RDA — within safe limits 3 studies — no high-quality reviews
Sodium
5 mg (1% DV)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Strontium
2 mg
1 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)

Other Ingredients

Hypromellose Sodium Croscarmellose Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Adults take 4 capsules daily, with a meal. Can also be taken as 2 capsules twice daily, with a meal.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Do not exceed recommended dose.

Warning: Do not take if you are pregnant or nursing. If you have a blood clotting issue, or if you are taking any medications, consult a healthcare professional before use.

Formulation Notes

Gluten free. No wheat, soy, dairy, gelatin, or artificial colors or flavors.

Bottled and tested in the USA

Vegetarian Gelatin free

Vegetarian Gelatin free

OsteoPrime with vitamin D3

To promote calcium absorption Supports bone health and bone density

Additional Information

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Vegetarian Gelatin free

Bottle made from 50% post-consumer recycled plastic

Formulated by Jonathan Wright, M.D. and Alan Gaby, M.D.

Metadata

Product Details

UPC / SKU7 63948 07722 9
DSLD Entry Date2025-03-25
Product TypeOther Combinations
FormCapsule
DSLD ID328135
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.