Home/ Supplements/ Vitamin A/ Clear Change Daily Essentials

Clear Change Daily Essentials

product on market Other (e.g. tea bag) Metagenics Safety: 98/100
98/100

This product looks safe

  • Niacin: 398mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 1135mg is 1135.0× the Tolerable Upper Intake Level (1.0mg)
  • 60% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains vitamins A, C, D, and E, which are supported by strong evidence for maintaining immune function and cellular health. These nutrients act as antioxidants and essential regulators of biological processes. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 398mg is 11.4× the Tolerable Upper Intake Level (35mg)

Folate: 1135mg is 1135.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Clear Change Daily Essentials
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Packet(s)
Serving Size
30
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin A
750 mcg (83% DV)
Vitamin C
383 mg (426% DV)
0.8 mcg (4% DV)
Within RDA (0.1× RDA) 608 studies (A:16, B:251)
44.8 mg (299% DV)
3.0× RDA — within safe limits 179 studies (A:3, B:90)
10 mg (833% DV)
8.3× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (385% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
398 mg (2488% DV)
Exceeds UL by 11.4× (UL: 35 mg) 196 studies (A:5, B:63)
27 mg (1588% DV)
20.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1135 mcg DFE (284% DV)
Exceeds UL by 1135.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
158 mcg (6583% DV)
65.8× RDA — above typical dose 139 studies (A:1, B:44)
66 mcg (220% DV)
2.2× RDA — within safe limits 27 studies (A:0, B:11)
33 mg (660% DV)
6.6× RDA — above typical dose 2 studies — no high-quality reviews
6.5 mg (59% DV)
Within RDA (0.6× RDA) 263 studies (A:6, B:134)
87 mcg (158% DV)
1.6× RDA — within safe limits 173 studies (A:0, B:67)
0.65 mg (72% DV)
Within RDA (0.7× RDA) 37 studies (A:0, B:11)
1.65 mg (72% DV)
Within RDA (0.7× RDA) 9 studies — no high-quality reviews
66 mcg (147% DV)
1.5× RDA — within safe limits 3 studies — no high-quality reviews
Sodium
40 mg (2% DV)
N-Acetyl L-Cysteine
642 mg
Market median: 500.0mg (82 products) 19 studies (A:1, B:6)
Cordyceps Mycelium Extract
200 mg
Artichoke Leaf Extract
167 mg
Watercress Aerial Parts Extract
133 mg
117 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Market median: 250.0mg (182 products) 10 studies (A:0, B:2)
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
50 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Broccoli Seed Extract
19.25 mg

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Magnesium Stearate Silica Microcrystalline Cellulose Cellulose Stearic Acid Silica Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose Hypromellose Sodium Copper Chlorophyllin Microcrystalline Cellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one packet daily for one to two months or as directed by your healthcare practitioner.

Warnings & Precautions

Warning: Do not use if taking blood thinning medications, antihypertensive medications, hypoglycemic medications and insulin, digoxin or nitroglycerin, or before surgery. Pregnant women and women who may become pregnant should not exceed 3,000 mcg of preformed vitamin A (retinyl palmitate) per day. Caution: If pregnant or nursing, or if taking medications, consult your healthcare practitioner before use.

Excessive vitamin A intake may increase the risk of birth defects. Tamper evident: Do not use if package is torn or open.

Formulation Notes

Clear Change Daily Essential is a premium packet containing 3 nutritional supplements designed to complement your daily foundation nutrition program and support daily detoxification following the Clear Change Metabolic Detoxification Program. This 1-month program features AdvaClear, GlutaClear, and Renagen DTX for targeted, daily support.

Each once-daily packet provides: Bifunctional detoxification support: AdvaClear supports vitality and health by supporting balanced activity of the Phase 1 and Phase 2 detoxification pathways. This formula provides methylated vitamin B12 and folic acid along with nutrients designed to enhance the activities of several liver detoxification enzymes. Antioxidant protection & detoxification support: GlutaClear features a blend of key ingredients, including antioxidant vitamins, designed to help boost the body's production of glutathione. Glutathione plays an important role in protecting the body against oxidative stress and protecting cellular health. Kidney health: Renagen DTX is a specific blend of nutrients and traditional herbs designed to support healthy kidney function.

The Metagenics Difference Metagentics is one of the few professional nutraceutical companies that formulates and evaluates nutritional products in clinical practice. Each Clear Change Daily Essential formula is science based and delivers optimized, targeted health support.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Each packet contains: 2 AdvaClear capsules (light brown), 1 GlutaClear tablet (white), and 1 Renagen DTX capsule (green).

Products included are non-GMO and gluten-free.

Clear Change Daily Essential provides advanced nutritional support for: Detoxification Bifunctional support Cellular protection Cellular health Antioxidant support Overall wellness Advanced detoxification support Practitioner recommended

Gluten-free Non-GMO

Additional Information

Not labeled for individual sale For product information call: US 800-692-940 0 Canada 800-268-6200 NPN: 80062144, 80049046, 80050486 1550330A

For more information, visit ClearChangeProgram.com Please Recycle

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Storage: Keep in a cool, dry place.

Metadata

Product Details

UPC / SKU7 55571 93967 8
DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandMetagenics
DSLD ID325700
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
Compare

Similar Products

Select-OB
Everett Laboratories · Other (e.g. tea bag)
100
Select-OB+DHA
Everett Laboratories · Other (e.g. tea bag)
100
Select-OB Berry Flavored Caplet
Exeltis USA · Other (e.g. tea bag)
100
Day 3 NeoLife Detox
NeoLife Nutritionals · Other (e.g. tea bag)
100
Advanced Diabetic Multivitamin Formula
Windmill Rx Premium Vitamins · Other (e.g. tea bag)
100
View all Vitamin A products →
Vitamin A research Best Vitamin A All Vitamin A products More from Metagenics View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.