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AdvaClear

product on market Capsule Metagenics Safety: 99/100
99/100

This product looks safe

  • Folate: 445mg is 445.0× the Tolerable Upper Intake Level (1.0mg)
  • 65% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains vitamins A, C, D, E, and thiamine, which are supported by strong evidence for maintaining immune function and cellular health. These nutrients act as antioxidants and essential cofactors in various metabolic processes. The formulation maintains a high safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 445mg is 445.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for AdvaClear
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
21
Servings
Other Combinations
Product Type
65%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
750 mcg (83% DV)
Vitamin C
133 mg (148% DV)
0.8 mcg (4% DV)
Within RDA (0.1× RDA) 608 studies (A:16, B:251)
44.6 mg (297% DV)
3.0× RDA — within safe limits 179 studies (A:3, B:90)
10 mg (833% DV)
8.3× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (385% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
23.3 mg (146% DV)
1.7× RDA — within safe limits 196 studies (A:5, B:63)
16.66 mg (980% DV)
12.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
445 mcg DFE (111% DV)
Exceeds UL by 445.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
33.4 mcg (1392% DV)
13.9× RDA — above typical dose 139 studies (A:1, B:44)
66 mcg (220% DV)
2.2× RDA — within safe limits 27 studies (A:0, B:11)
33.3 mg (666% DV)
6.7× RDA — above typical dose 2 studies — no high-quality reviews
6.5 mg (59% DV)
Within RDA (0.6× RDA) 263 studies (A:6, B:134)
50 mcg (91% DV)
Within RDA (0.9× RDA) 173 studies (A:0, B:67)
0.66 mg (73% DV)
Within RDA (0.7× RDA) 37 studies (A:0, B:11)
1.66 mg (72% DV)
Within RDA (0.7× RDA) 9 studies — no high-quality reviews
66 mcg (147% DV)
1.5× RDA — within safe limits 3 studies — no high-quality reviews
Sodium
40 mg (2% DV)
Artichoke Leaf Extract
167 mg
Watercress Aerial Parts Extract
133 mg
117 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Market median: 250.0mg (182 products) 10 studies (A:0, B:2)
N-Acetyl-L-Cysteine
67 mg
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
50 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Hydroxypropylmethylcellulose Microcrystalline Cellulose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Warnings & Precautions

Practitioner exclusive

Formulation Notes

Experience a Clear Change The Clear Change Program, recommended by your healthcare provider, includes key nutritional support you need to start helping you feel your best. Get started today!

These products are non-GMO and gluten-free.

Natural chai flavor with other natural flavors

Gluten free Non-GMO

The Metagenics difference Research-based formulas and scientifically designed food plans Formulas manufactured in high quality, triple GMP-certified facilities

Betatene mixed carotenoids

No MSG Certified gluten free GFCO.org (Gluten-Free Certification Organization)

Vegetarian capsule

Contains no more than 4% caffeine

Additional Information

This box contains UltraClear Renew powder AdvaClear capsules Free shaker cup Program guide with menu plan Webinar invitation

Please recycle

Online program support tools For more information, visit ClearChangeProgram.com

Certified gluten free GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 55571 94434 4
DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormCapsule
BrandMetagenics
DSLD ID323340
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.