🟢 99/100

This product looks safe

  • Folate: 445mg is 445.0× the Tolerable Upper Intake Level (1.0mg)
  • 65% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 445mg is 445.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
38 Servings
Other Combinations Product Type
65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
750 mcg (83% DV)
Vitamin C
133 mg (148% DV)
0.8 mcg (4% DV)
✅ Within RDA (0.1× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0008mg UL 0.1mg
44.6 mg (297% DV)
✅ 3.0× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 44.6mg UL 1000mg
10 mg (833% DV)
📊 8.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 10mg
5 mg (385% DV)
📊 3.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 5mg
23.3 mg (146% DV)
✅ 1.7× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 23.3mg UL 35mg
16.66 mg (980% DV)
📊 12.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 16.66mg UL 100mg
445 mcg DFE (111% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 445.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 445mg UL 1.0mg
33.4 mcg (1392% DV)
📊 13.9× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.0334mg
66 mcg (220% DV)
✅ 2.2× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.066mg
33.3 mg (666% DV)
📊 6.7× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 33.3mg
6.5 mg (59% DV)
✅ Within RDA (0.6× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 6.5mg UL 40mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
0.66 mg (73% DV)
✅ Within RDA (0.7× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.66mg UL 10mg
1.66 mg (72% DV)
✅ Within RDA (0.7× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 1.66mg UL 11mg
66 mcg (147% DV)
✅ 1.5× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.066mg UL 2mg
Sodium
40 mg (2% DV)
Artichoke Leaf Extract
167 mg
Watercress Aerial Parts Extract
133 mg
117 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 117mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
📊 Market median: 250.0mg (182 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 87.5mg
N-Acetyl-L-Cysteine
67 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 56mg
50 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 50mg

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Magnesium Stearate Silica

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take two capsules once daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Excess vitamin A intake may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 3,000 mcg of preformed vitamin A (Retinyl palmitate) per day. Caution: If pregnant or nursing, or taking medications, consult your healthcare practitioner before use.

Keep out of the reach of children.

Tamper evident: Do not use if safety seal is missing or broken.

To report adverse events call 866-649-4334.

🧪 Formulation Notes

AdvaCleanse supports daily detoxification for optimal vitality and health.

This formula provides methylated B12 and folate along with biofunctional nutritional support designed to enhance the activities of several liver detoxification enzymes and support Phase I and Phase II detoxification pathways.

This product is non-GMO and gluten-free.

Daily support for balanced detoxification

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Product Details

DSLD Entry Date 2024-10-24
Product Type Other Combinations
Form Capsule
DSLD ID 313102
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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