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Daily One

product on market Other (e.g. tea bag) Puritan's Pride Safety: 99/100
99/100

This product looks safe

  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • 71% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The profile includes essential vitamins A, C, D, E, and thiamine, which are supported by strong evidence for maintaining immune function and cellular health. These nutrients play critical roles in metabolic processes and antioxidant defense. The formulation maintains a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Daily One
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
60
Servings
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1500 mcg (167% DV)
Vitamin C
120 mg (133% DV)
50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
20.1 mg (134% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
10 mg (833% DV)
8.3× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (769% DV)
7.7× RDA — above typical dose 13 studies (A:0, B:1)
25 mg (156% DV)
1.8× RDA — within safe limits 196 studies (A:5, B:63)
10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
666 mcg DFE (167% DV)
Exceeds UL by 666.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
10 mg (200% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews
Calcium
50 mg (4% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
50 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (364% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
200 mcg (571% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
15 mcg (33% DV)
Within RDA (0.3× RDA) 3 studies — no high-quality reviews
Potassium
1 mg (1% DV)
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)

Other Ingredients

Cellulose Citrus Bioflavonoids Gelatin Kelp natural Palm leaf glaze Rose Hips Rutin Silica Titanium Dioxide Magnesium Stearate Stearic Acid
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Directions: For adults, take one (1) caplet daily, preferably with a meal.

Warnings & Precautions

Contains bioengineered food ingredients.

Warning: Not intended for use by pregnant or nursing women. If you are taking any medications, planning any medical or surgical procedure, have any medical condition, or are planning to undergo any clinical lab testing, consult your doctor before use. Some supplements may interact with certain medications and/or interfere with certain lab tests.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

No artificial flavor, no sugar, no milk, no lactose, no gluten, no wheat, no yeast.

Iron Free

Timed Release Long Acting

Additional Information

Store at room temperature.

To reorder item # 19477 www.puritan.com 1-800-645-1030

QA Quality Assured

Metadata

Product Details

UPC / SKU0 25077 19477 3
DSLD Entry Date2023-05-24
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandPuritan's Pride
DSLD ID286019
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.