🟢 99/100

This product looks safe

  • Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrate
1 Gram(s) (1% DV)
Vitamin C
100 mg (111% DV)
25 mg (2084% DV)
📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 25mg
25 mg (1923% DV)
📊 19.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 25mg
25 mg (156% DV)
✅ 1.8× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 25mg UL 35mg
25 mg (1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
1360 mcg DFE (340% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1360.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1360mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
47 mg (954% DV)
📊 9.4× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 47mg
Calcium
163 mg (13% DV)
350 mg (83% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 350mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
3 mg (130% DV)
✅ 1.3× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 3mg UL 11mg
Sodium
5 mg (1% DV)
Gamma-Aminobutyric Acid
600 mg
250 mg
📊 Market median: 500.0mg (223 products) 📚 22 studies (Tier A: 0, B: 1)
This product: 250mg
Eleuthero root extract
200 mg
150 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 150mg
Gotu Kola Whole Plant Extract
100 mg
Lemon Balm
100 mg
Relora
100 mg
100 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 100mg
📊 Market median: 500.0mg (138 products) 📚 2 studies — no high-quality reviews
This product: 100mg
60 mg
📊 Market median: 300.0mg (214 products) 📚 23 studies (Tier A: 0, B: 6)
This product: 60mg
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 50mg
50 mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 50mg
📊 Market median: 420.0mg (127 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 50mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 30mg
30 mg
📊 Market median: 650.0mg (87 products) 📚 1 studies — no high-quality reviews
This product: 30mg

Other Ingredients

Stearic Acid Dibasic Calcium Phosphate Acacia Gum modified Cellulose Gum Silica Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: 1 to 3 tablets daily. Best if taken between meals. If stomach is sensitive, take with meals.

⚠️ Warnings & Precautions

Warning: Excessive consumption of this product may impair ability to drive or operate heavy equipment. Not recommended for consumption with alcoholic beverages.

Do not use this product while taking any medication or if you have a medical condition without the advice of your physician or pharmacist. St. Johns Wort is known to interfere with many prescription and non-prescription drugs, and it may also cause increased photosensitivity.

Limit exposure to UV radiation.

If you are pregnant, may become pregnant, or breastfeeding, consult your healthcare professional before using this product.

Do not use if tamper-evident seal is broken or missing.

Keep out of the reach of children.

California consumers: Warning: Reproductive harm - www.P65warnings.ca.gov/food

🧪 Formulation Notes

Bio Align

Helps reduce anxiety & stress Supports calm focus

Product Details

UPC / SKU 0 21078 01131 6
DSLD Entry Date 2022-10-24
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 274525
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
View all evidence for Riboflavin →

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