Home/ Supplements/ Folate/ Multivitamin + 15 mg L-Methylfolate

Multivitamin + 15 mg L-Methylfolate

product on market Capsule MethylPro Safety: 96/100
96/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 25mg is 25.0× the Tolerable Upper Intake Level (1.0mg)
  • 74% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formulation contains essential vitamins A, C, D3, E, and thiamine, which support immune function and cellular metabolism. There is strong evidence for the role of these nutrients in maintaining general health. The product maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 25mg is 25.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Multivitamin + 15 mg L-Methylfolate
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
74%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
900 mcg RAE (100% DV)
Vitamin C
150 mg (167% DV)
50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
67 mg (447% DV)
4.5× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
10 mg (833% DV)
8.3× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (769% DV)
7.7× RDA — above typical dose 13 studies (A:0, B:1)
50 mg NE (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg DFE (6250% DV)
Exceeds UL by 25.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
100 mcg (333% DV)
3.3× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
100 mcg (67% DV)
Within RDA (0.7× RDA) 245 studies (A:4, B:133)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
100 mcg (182% DV)
1.8× RDA — within safe limits 173 studies (A:0, B:67)
5 mg (217% DV)
2.2× RDA — within safe limits 9 studies — no high-quality reviews
100 mcg (286% DV)
2.9× RDA — within safe limits 199 studies (A:1, B:55)
75 mcg (167% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
55 mg (10% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)

Other Ingredients

Vegetable Cellulose Capsule
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Directions: One (1) capsule daily with meals as a dietary supplement, or as directed by a healthcare professional.

Warnings & Precautions

Keep tightly closed in a cool, dry place, out of the reach of children.

Vitamin E is derived from soy oil.

Formulation Notes

Egg free Gluten free Free of nuts Dairy free

Manufactured in a GMP Compliant Facility

Professional strength L-Methylfolate

Additional Information

Keep tightly closed in a cool, dry place, out of the reach of children.

Metadata

Product Details

UPC / SKU8 38287 00818 7
DSLD Entry Date2022-09-22
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
BrandMethylPro
DSLD ID274166
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.