🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 78% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Tablet(s) Serving Size
Other Combinations Product Type
78% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
7500 IU (150% DV)
Vitamin C
650 mg (1080% DV)
900 IU (225% DV)
✅ 1.5× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.022500000000000003mg UL 0.1mg
200 IU (670% DV)
📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 134.0mg UL 1000mg
13.5 mg (900% DV)
📊 11.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 13.5mg
13.5 mg (790% DV)
📊 10.4× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 13.5mg
20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
16 mg (800% DV)
📊 12.3× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 16mg UL 100mg
500 ug (125% DV)
✅ 1.2× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.5mg UL 1.0mg
100 ug (1670% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
150 ug (50% DV)
📊 5.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.15mg
45 mg (450% DV)
📊 9.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 45mg
30 ug (40% DV)
✅ Within RDA (0.2× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.03mg
OLIVOL(R)
15 mg
✅ 1.1× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 17mg UL 1000mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 99mg
75 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 75mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 50mg UL 3500mg
N-ACETYL L-CYSTEINE
50 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 6mg UL 1200mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 7.5mg
300 ug
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.3mg
500 ug
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 0.5mg

Other Ingredients

Microcrystalline Cellulose pregelatinized Starch Croscarmellose Sodium Ascorbyl Palmitate Alpha-Lipoic Acid Dextrin Silicon Dioxide Dextrose Soy Lecithin Sodium Citrate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Kosher

Product Information

📋 Directions for Use

DIRECTIONS: TAKE TWO (2) TABLETS TWICE DAILY, PREFERABLE WITH FOOD.

⚠️ Warnings & Precautions

CONTAINS SOY.

KEEP OUT OF REACH OF CHILDREN.

CONSULT YOUR PHYSICIAN IF YOU ARE PREGNANT, NURSING, TAKING A PRESCRIPTION DRUG, OR HAVE A MEDICAL CONDITION.

THERE IS A SAFETY SEAL UNDER THE CAP. DO NOT USE IF THE SAFETY SEAL IS BROKEN OR MISSING.

🧪 Formulation Notes

Kosher

CONTAINS SOY.

Top-rated daily vitamin and antioxidant supplement for adults

Additional Information

Essentials

ESSENTIAL HEALTH Complete, effective combinations of nutrients are needed to provide a foundation for good health. For the best results, Mega Antioxidant should be taken with Chelated Mineral. The following are a few examples of how Mega Antioxidant offers broad, balanced nutritional support for every aspect of optimal health:*

HEART HEALTH • High levels of antioxidants in the blood have been shown to help maintain cardiovascular health.* • Vitamin E and mixed tocopherols play a critical role in protecting LDL and cell membranes from oxidation, keeping arteries healthy. Vitamin C is also helpful in maintaining healthy veins and arteries by supporting healthy tissue growth and strengthening collagen.* • The B vitamins, especially riboflavin, folate, and vitamins B6 and B12, are fundamental to the maintenance of healthy levels of the amino acid homocysteine, provided they are healthy to begin with. Homocysteine levels have been linked to heart health.* • Vitamin B12 is also necessary for the health of red blood cells and DNA, the genetic material in all cells. Those who do not take a supplement containing vitamin B12 are twice as likely to be vitamin B12 deficient as supplement users, regardless of age group. Coenzyme Q10 plays a key role in producing cellular energy, demand for which is especially high in the heart, making this an important nutrient for cardiovascular health. In addition, cellular-energy production requires a full spectrum of B vitamin activities.* • Vitamin D deficiency has been linked to an increased risk of heart disease.

VISION • Mixed carotenoids, including beta carotene, lutein, and other antioxidants, help maintain good vision.* Lutein selectively accumulates in tissues in the eye to help protect against damaging UV rays. • Vitamin C is especially important for the retina, where concentration of this essential nutrient is significantly higher than in the blood.

IMMUNITY • By helping to maintain the integrity of all cell membranes, along with the digestive system and lungs, beta carotene is important for strong immunity. • Vitamins B6, B12, and folate are critical for producing immune cells. • Vitamin E, vitamin D, as well as vitamin C are well known for their immune-cell supporting properties.

NSF(R) GMP Registered

K

your health. your life. your way.

ANTIOXIDANTS - YOUR CELLS' SUPERHEROES Cell-damaging oxidative stress is caused by free radicals that come from normal cellular metabolism, exposure to pollution and toxins, stress, and poor diet and lifestyle habits. Free radicals attack our cells, gradually chipping away at their integrity, resulting in an eventual decline in health. Antioxidants neutralize the activity of free radicals to protect the integrity of our cells, which impacts every part of our body. Mega Antioxidant provides advanced levels of a wide range of antioxidants: • Vitamins C and E, along with beta carotene (which naturally converts into vitamin A only as needed, providing the benefits of vitamin A without the risk of toxicity), are powerful antioxidants that also reinforce the activity of the others. • Flavonoids and phenolic compounds, which are abundant in fruits and vegetables, not only provide important protection against oxidative stress, they also complement and extend the activities of other antioxidants as well. A unique bioflavonoid complex—including quercetin, rutin, hesperidin, green tea, bilberry, pomegranate, and cinnamon—plus turmeric all work to inhibit the activity of free radicals.* • Certain polyphenolic antioxidants found in olives are not present in other common dietary sources.

LABORATORY TESTED, QUALITY GUARANTEED. MEETS USP SPECIFICATIONS FOR POTENCY, UNIFORMITY, AND DISINTEGRATION, WHERE APPLICABLE.

STORE BELOW 25(0)C

MADE IN USA

Mega Antioxidant supplies precisely balanced levels of high-quality, highly bioavailable vitamins and antioxidants that work together to protect your health.*

References • Age-Related Eye Disease Study Research Group. A randomized, placebocontrolled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. 2001. Arch Ophthalmol 119(10):1417-36. • Barringer TA, Kirk JK, Santaniello AC, Foley KL, Michielutte R. Effect of a multivitamin and mineral supplement on infection and quality of life. A randomized, double-blind, placebo-controlled trial. 2003. Ann Intern Med 138(5):365-71. • Cosgrove MC, Franco OH, Granger SP, Murray PG, Mayes AE. Dietary nutrient intakes and skin-aging appearance among middle-aged American women. 2007. AJCN 86(4):1224-31. • Girodon F, Galan P, Monget AL, Boutron-Ruault MC, Brunet-Lecomte P, Preziosi P, Arnaud J, Manuguerra JC, Herchberg S. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized controlled trial. 1999. Arch Intern Med 159(7):748-54. • Heinrich U, Gartner C, Wiebusch M, Eichler O, Sies H, Tronnier H, Stahl W. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. 2003. J Nutr 133(1):98-101. • Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. 2004. Am J Clin Nutr 79(3):362-371. • Kaikkonen J, Tuomainen TP, Nyyssonen K, Salonen JT. Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels. 2002. Free Radic Res 36(4):389-97. • Lutsenko EA, Carcamo JM, Golde DW. Vitamin C Prevents DNA Mutation Induced by Oxidative Stress. 2002. J Biol Chem 277(19):16895-9. • Merchant AT, Hu FB, Spiegelman D, Willett WC, Rimm EB, Ascherio A. The use of B vitamin supplements and peripheral arterial disease risk in men are inversely related. 2003. J Nutr 133(9):2863-7. • Meydani SN, Meydani M, Blumberg JB, Leka LS, Siber G, Loszewski R, Thompson C, Pedrosa MC, Diamond RD, Stollar BD. Vitamin E supplementation and in vivo immune response in healthy elderly subjects: a randomized controlled trial. 1997. JAMA 277(17):1380-6. • Placzek M, Gaube S, Kerkmann U, Gilbertz KP, Herzinger T, Haen E, Przybilla B. Ultraviolet B-induced DNA damage in human epidermis is modified by the antioxidants ascorbic acid and D-alpha-tocopherol. 2005. J Invest Dermatol 124(2):304-7. • AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. 2004. Curr Med Chem 11(9):1135-46. •Sreejayan, Rao MN. Curcuminoids as potent inhibitors of lipid peroxidation. 1994. J Pharm Pharmacol, 46(12): 1013-6.

ITEM #103

LB.000243

BONE HEALTH • Vitamin D helps in the development and maintenance of mineral-rich bones and teeth. Healthy levels of this important nutrient are a key part of minimizing age-related bone loss. It also supports muscle strength.* RESPIRATORY FUNCTION • Lycopene and the combination of vitamin C and bioflavonoids support health maintenance for many organs. ENERGY, NUTRIENT METABOLISM • Several B vitamins are involved in energy metabolism, helping to convert the carbohydrates, fats, and proteins we eat into fuel for our cells. DETOXIFICATION • Vitamin C helps to conserve glutathione, which is produced in the liver. The natural detoxification process can create a great deal of oxidative stress, especially in the liver. Intracellular glutathione is one of the most important antioxidants for defending cell health, and it acts as a primary detoxification element. • N-acetyl l-cysteine can also help boost glutathione. • Choline and inositol help metabolize fats in the liver. BRAIN AND NERVE FUNCTION • B vitamins are important for brain and nerve support. Folate is especially important for women who may have children. Women who consume healthful diets with adequate folate throughout their childbearing years may reduce their risk of having a child with a birth defect of the brain or spinal cord. Sources of folate include fruits, vegetables, whole grain products, fortified cereals, and dietary supplements.* • Choline supports transmission of nerve impulses from the brain throughout the central nervous system. It is also important for memory support. SKIN, HAIR, NAILS • Antioxidants, such as vitamin E, help defend your cells against the oxidative stress caused by sunlight, pollution, and stress, which can all prematurely age the skin. • Lycopene, lutein, and beta carotene play a role in supporting healthy, glowing skin. • Inositol, as well as biotin and pantothenic acid, are fundamental to the growth of healthy skin, hair, and nails. • Vitamin C is essential for synthesizing collagen, proteins that provide elasticity to our connective tissues (also important for the maintenance of muscle, joint, and tendon function). WHY MEGA ANTIOXIDANT? Because it is one half of the Essentials—the top-rated supplements in the world—you can trust that Mega Antioxidant is the best multivitamin and antioxidant supplement you can use to protect your health every day. Formulated by a team of nutritional-science experts using readily bioavailable forms of each nutrient, the USANA Essentials surpass virtually every competitor for completeness, potency, and quality. Our own in-house study also revealed that the Essentials provided increased levels of select nutrients over a longer period of time than some competitive products. USANA is proud to be one of only a handful of manufacturers who makes products in our own state-of-the-art facility, which allows us to oversee the entire production cycle to ensure that our products deliver only the safest, most effective formulas for you and your family.

Product Details

DSLD Entry Date 2013-11-25
Product Type Other Combinations
Form Tablet or Pill
Brand USANA
DSLD ID 26916
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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