Women's 50+ Advanced by up&up — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
73% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size

Multi-Vitamin and Mineral (MVM) Product Type

73% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

3500 IU (70% DV)

Vitamin C

120 mg (200% DV)

Vitamin D

1000 IU (250% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

30 IU (100% DV)

✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20.1mg UL 1000mg

Vitamin K

20 mcg (25% DV)

✅ Within RDA (0.2× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.02mg

Thiamine

4.5 mg (300% DV)

📊 3.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 4.5mg

Riboflavin

3.4 mg (200% DV)

✅ 2.6× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 3.4mg

Niacin

20 mg (100% DV)

✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

6 mg (300% DV)

📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 6mg UL 100mg

Folic Acid

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

25 mcg (417% DV)

📊 10.4× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.025mg

Biotin

30 mcg (10% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

15 mg (150% DV)

✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 15mg

Calcium

500 mg (50% DV)

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

50 mg (13% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 50mg

Zinc

24 mg (160% DV)

✅ 2.2× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 24mg UL 40mg

Selenium

27 mcg (39% DV)

✅ Within RDA (0.5× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.027mg UL 0.4mg

Copper

2.2 mg (110% DV)

✅ 2.4× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2.2mg UL 10mg

Manganese

4.2 mg (210% DV)

✅ 1.8× RDA — within safe limits 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 4.2mg UL 11mg

Chromium

180 mcg (150% DV)

📊 5.1× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.18mg

Molybdenum

90 mcg (120% DV)

✅ 2.0× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.09mg UL 2mg

Other Ingredients

Calcium Carbonate Dicalcium Phosphate Ascorbic Acid Magnesium Oxide Microcrystalline Cellulose Croscarmellose Sodium DL-Alpha-Tocopheryl Acetate Polyvinyl Alcohol Zinc Oxide Stearic Acid Niacinamide Calcium Pantothenate Titanium Dioxide color Polyethylene Glycol Manganese Sulfate Silicon Dioxide Talc Magnesium Stearate Crospovidone Pyridoxine Hydrochloride Thiamine Mononitrate Cupric Sulfate Riboflavin Vitamin A Acetate FD&C Yellow #6 Aluminum Lake Chromium Chloride FD&C Yellow #5 Aluminum Lake Folic Acid Beta-Carotene Potassium Iodide Sodium Molybdate Sodium Selenate FD&C Blue #2 Aluminum Lake Biotin Cholecalciferol Phytonadione Cyanocobalamin

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Women ONLY Gluten Free

Product Information

📋 Directions for Use

Directions: Adults, take one tablet daily with food.

⚠️ Warnings & Precautions

Caution: If you are taking any medication or have a medical condition, consult a doctor before taking this product. If you are pregnant or nursing a baby, ask a doctor before using this product.

Keep out of reach of children.

Do not use if printed seal under cap is broken or missing.

🧪 Formulation Notes

Helps support cell health bone health heart health eye health

With 20% DV more Vitamin A (3500 IU vs. 2500 IU), 100% DV more Vitamin C (120 mg vs. 60 mg), 25% DV more Vitamin E (30 IU vs. 22.5 IU), 10% DV more zinc (24 mg vs. 22.5 mg), 10% DV more selenium (27 mcg vs. 20 mcg), 10% DV more copper (2.2 mg vs. 2 mg) , and 10% DV more manganese (4.2 mg vs. 4 mg) than previous formula.

Gluten free

Specialized formula with nutrients that matter to women 50+ to support: cell health with antioxidants: beta-carotene, vitamins C, E, zinc, manganese, copper and selenium Bone strength with calcium, vitamin D and magnesium Joint health with vitamin C to support collagen formation. Normal blood pressure with vitamin C, calcium and magnesium Heart health with vitamins B6, B12, C, E and folic acid Eye health with vitamins A, C, E and zinc Immune health with vitamins A, C, E and selenium Energy metabolism with b vitamins and chromium Blood pressure levels already within the normal range

A complete multivitamin with nutrients that matter to women 50+ Women over 50 don't have to settle for an all-purpose multivitamin which may not meet their unique nutritional needs. This product is formulated specifically to help support the health of women 50+, including cell health. Now it has more of 7 antioxidants. Antioxidants help protect cells in the body from free radical damage.

daily multivitamin

Does not contain iron.

Additional Information

Store in a dry place at room temperature (59 degrees F-86 degrees F).

Compare to ingredients in One a day Women's 50+ healthy advantage

Product Details

UPC / SKU 0 70030 62128 5

DSLD Entry Date 2020-01-25

Product Type Multi-Vitamin and Mineral (MVM)

Form Tablet or Pill

Brand up&up

DSLD ID 211621

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →