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Essential Capsules

product on market Capsule Blueprint Bryan Johnson Safety: 97/100
97/100

This product looks safe

  • Folate: 200mg is 200.0× the Tolerable Upper Intake Level (1.0mg)
  • Nicotinamide Riboside Chloride: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)
  • 62% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The profile contains essential B vitamins and fat-soluble vitamins D and E, which support cellular energy metabolism and immune function. There is strong evidence for the roles of these nutrients in maintaining general physiological health. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 200mg is 200.0× the Tolerable Upper Intake Level (1.0mg)

Nicotinamide Riboside Chloride: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Essential Capsules
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Veggie Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
62%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
67 mg (447% DV)
4.5× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
1.1 mg (92% DV)
Within RDA (0.9× RDA) 76 studies (A:0, B:33)
1.4 mg (108% DV)
1.1× RDA — within safe limits 13 studies (A:0, B:1)
15 mg (94% DV)
1.1× RDA — within safe limits 196 studies (A:5, B:63)
1.4 mg (82% DV)
1.1× RDA — within safe limits 114 studies (A:3, B:35)
200 mcg DFE (50% DV)
Exceeds UL by 200.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
125 mcg (5208% DV)
52.1× RDA — above typical dose 139 studies (A:1, B:44)
50 mg (167% DV)
1666.7× RDA — above typical dose 27 studies (A:0, B:11)
6 mg (120% DV)
1.2× RDA — within safe limits 2 studies — no high-quality reviews
Calcium
50 mg (4% DV)
200 mcg (133% DV)
1.3× RDA — within safe limits 245 studies (A:4, B:133)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
28 mcg (51% DV)
Within RDA (0.5× RDA) 173 studies (A:0, B:67)
1 mg (43% DV)
Within RDA (0.4× RDA) 9 studies — no high-quality reviews
Exceeds UL by 8.6× (UL: 35 mg) 196 studies (A:5, B:63)
Broccoli Seed Extract
200 mg
Fisetin
100 mg
Luteolin
100 mg
50 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)
Market median: 80.0mg (20 products) 337 studies (A:8, B:183)
Spermidine
10 mg
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Lithium
1 mg
Claims

Label Claims — Verification

Unverified No Claim
Info

Product Information

Metadata

Product Details

DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormCapsule
DSLD ID328204
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.