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GI Sustain

product on market Powder Metagenics Safety: 99/100
99/100

This product looks safe

  • Folate: 235mg is 235.0× the Tolerable Upper Intake Level (1.0mg)
  • 42% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The product provides foundational macronutrients and Vitamin A, which supports immune function and cellular health. There is strong evidence for the roles of these basic nutrients in maintaining general physiological processes. The overall ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 235mg is 235.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for GI Sustain
Open Full PDF View on NIH DSLD →
Details

Label Data

49 Gram(s)
Serving Size
14
Servings
Other Combinations
Product Type
42%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
170 Calorie(s)
Total Fat
5 Gram(s) (6% DV)
Total Carbohydrates
24 Gram(s) (13% DV)
Protein
13 Gram(s) (26% DV)
Vitamin A
1200 mcg (133% DV)
Vitamin C
102 mg (113% DV)
1.2 mcg (6% DV)
Within RDA (0.1× RDA) 608 studies (A:16, B:251)
33.5 mg (223% DV)
2.2× RDA — within safe limits 179 studies (A:3, B:90)
0.5 mg (42% DV)
Within RDA (0.4× RDA) 76 studies (A:0, B:33)
0.6 mg (46% DV)
Within RDA (0.5× RDA) 13 studies (A:0, B:1)
10 mg (63% DV)
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
0.7 mg (41% DV)
Within RDA (0.5× RDA) 114 studies (A:3, B:35)
235 mcg DFE (59% DV)
Exceeds UL by 235.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
2.1 mcg (88% DV)
Within RDA (0.9× RDA) 139 studies (A:1, B:44)
105 mcg (350% DV)
3.5× RDA — above typical dose 27 studies (A:0, B:11)
100 mg (2000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
300 mg (23% DV)
Iron
3.6 mg (20% DV)
180 mg (14% DV)
Within RDA (0.3× RDA) 13 studies (A:0, B:3)
120 mg (29% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
7.5 mg (68% DV)
Within RDA (0.7× RDA) 263 studies (A:6, B:134)
0.5 mg (56% DV)
Within RDA (0.6× RDA) 37 studies (A:0, B:11)
1.3 mg (57% DV)
Within RDA (0.6× RDA) 9 studies — no high-quality reviews
75 mcg (214% DV)
2.1× RDA — within safe limits 199 studies (A:1, B:55)
Sodium
20 mg (1% DV)
Potassium
300 mg (6% DV)
Isomalto-Oligosaccharides
3.4 Gram(s)
500 mg
Market median: 420.0mg (227 products)
Glycine
100 mg
100 mg
Market median: 500.0mg (193 products) 7 studies — no high-quality reviews
35 mg
Market median: 500.0mg (159 products)
L-Threonine
34 mg
L-Cysteine
25 mg

Other Ingredients

Rice Protein Concentrate Rice Syrup, Solids Apple Fiber Olive Oil Medium Chain Triglyceride Acacia Gum Silica Natural Flavors Rice Maltodextrin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Blend, shake, or briskly stir about 2 level scoops (49 grams) of GI Sustain into 8 ounces of chilled water or juice twice daily or as directed by your healthcare practitioner. For highly sensitive individuals, consider reducing consumption to 1/2 to 1 scoop with 4 to 5 ounces of chilled water or juice daily during the first 3 to 4 days before starting a full daily dose.

Warnings & Precautions

Warning: Excess vitamin A intake may increase the risk of birth defects.

Pregnant women and women who may become pregnant should not exceed 3,000 mcg of preformed vitamin A (retinyl palmitate) per day unless instructed to do so by a healthcare practitioner

Caution: Keep out of the reach of children.

Tamper evident: Do not use if safety seal is missing or broken.

Practitioner Exclusive

Formulation Notes

GI Sustain is designed to provide gastronintestinal nutritional support. The formula is uniquely designed to help promote the growth of beneficial bacteria by including prebiotic nutrients, combined with readily digestible macronutrients. Nourishes the cells of the intestinal mucosa

GI Sustain features L-glutamine and prebiotic isomalto-oligosaccharides (IMOS) to promote gastrointestinal health. Features rice protein concentrate supplemented with L-lysine and L-threonine for an naturally-derived amino acid profile Formulated with rice syrup solids as a naturally-derived energy source Features medium-chain triglycerides, a readily absorbed and metabolized lipid source Features prebiotic IMOs to selectively nourish beneficial bacteria, including lactobacilli and bifidobacteria Formulated with zinc and L-glutamine to nutritionally support gastrointestinal mucosa integrity Features methylated B12 and calcium L-5 methyltetrahydrofolate, a bioavailable folate

This product is non-GMO and gluten-free.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Gastrointestinal nutritional support

Formulated for neutral taste Naturally flavored

Gluten-free Non-GMO

No MSG

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Contents sold by weight, not volume. Some settling may occur during shipping and handling. Serving size is measured by weight with a scoop included for your convenience. The amount of product contained in two scoops may be above or below 49 grams due to variations in handling and product density.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 55571 93469 7
DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormPowder
DSLD ID323360
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.