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Macushield

product on market Capsule Douglas Laboratories Safety: 89/100
89/100

This product is generally safe

  • Niacin/Niacinamide: 60mg is 1.7× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 59% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains vitamins A, C, E, and B-complex, which are supported by strong evidence for their roles in antioxidant protection and cellular health. These ingredients collectively help neutralize free radicals and support ocular function. The evidence coverage for this specific combination is limited, though the safety profile remains high.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin/Niacinamide: 60mg is 1.7× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Macushield
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
59%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
15000 IU (300% DV)
Vitamin C
500 mg (833% DV)
200 IU (667% DV)
8.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
25 mg (1667% DV)
20.8× RDA — above typical dose 76 studies (A:0, B:33)
25 mg (1471% DV)
19.2× RDA — above typical dose 13 studies (A:0, B:1)
60 mg (300% DV)
Exceeds UL by 1.7× (UL: 35 mg) 196 studies (A:5, B:63)
25 mg (1250% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
200 mcg (50% DV)
Within RDA (0.5× RDA) 226 studies (A:10, B:105)
100 mcg (1667% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
100 mg (1000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
100 mg (10% DV)
200 mg (50% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
20 mg (133% DV)
1.8× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
3 mg (150% DV)
3.3× RDA — above typical dose (UL: 10 mg) 37 studies (A:0, B:11)
3 mg (150% DV)
1.3× RDA — within safe limits 9 studies — no high-quality reviews
400 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Proprietary Blend
50 mg
N-Acetyl-L-Cysteine
200 mg
Market median: 100.0mg (120 products)
Market median: 120.0mg (440 products) 191 studies (A:1, B:71)
L-Glutathione
25 mg
50 mg
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
15 mg
Market median: 500.0mg (19 products)
Hesperidin
10 mg
10 mg
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
1 mg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)

Other Ingredients

Cellulose Gelatin Silica Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, adults take 6 capsules daily or as directed by your healthcare professional. This product is best taken with meals.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Formulation Notes

This product contains NO yeast, wheat, gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Formula #85014

Metadata

Product Details

UPC / SKU3 10539 85014 5
DSLD Entry Date2014-03-25
Product TypeOther Combinations
FormCapsule
BrandDouglas Laboratories
DSLD ID31040
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.