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Metabolic Co-Factor

product on market Capsule Allergy Research Group Safety: 99/100
99/100

This product looks safe

  • Niacin: 210mg is 6.0× the Tolerable Upper Intake Level (35mg)
  • 71% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The formula contains essential vitamins including A, C, D3, E, and thiamine, which support immune function and cellular energy metabolism. There is strong evidence for the roles of these nutrients in maintaining general physiological health. The profile maintains a high safety score, though overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 210mg is 6.0× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Metabolic Co-Factor
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Capsule(s)
Serving Size
30
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
2500 IU (50% DV)
Vitamin C
384 mg (640% DV)
800 IU (200% DV)
1.3× RDA — within safe limits 608 studies (A:16, B:251)
100 IU (333% DV)
4.5× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
20 mg (1330% DV)
16.7× RDA — above typical dose 76 studies (A:0, B:33)
20 mg (1180% DV)
15.4× RDA — above typical dose 13 studies (A:0, B:1)
210 mg (1050% DV)
Exceeds UL by 6.0× (UL: 35 mg) 196 studies (A:5, B:63)
25 mg (1250% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
500 mcg (167% DV)
16.7× RDA — above typical dose 27 studies (A:0, B:11)
200 mg (2000% DV)
40.0× RDA — above typical dose 2 studies — no high-quality reviews
250 mg (63% DV)
Within RDA (0.6× RDA) 316 studies (A:8, B:159)
30 mg (200% DV)
2.7× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
0.5 mg (25% DV)
Within RDA (0.6× RDA) 37 studies (A:0, B:11)
10 mg (500% DV)
4.3× RDA — above typical dose (UL: 11 mg) 9 studies — no high-quality reviews
1 mg (833% DV)
28.6× RDA — above typical dose 199 studies (A:1, B:55)
1 mg (1330% DV)
22.2× RDA — above typical dose (UL: 2 mg) 3 studies — no high-quality reviews
2 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
200 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose L-Leucine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use As a dietary supplement, 6 capsules daily, or as directed by a healthcare practitioner.

Warnings & Precautions

Taking more than 400 mcg of selenium per day from all sources should only be done under the guidance of a healthcare professional.

Not labeled for sale in California.

Formulation Notes

Now with Quatrefolic, the patented glucosamine salt of 5-methyltetrahydrofolate.

Additional Information

Metabolic Co-Factor is a multiple vitamin and mineral formula, developed by Dr. Leo Galland, M.D., to support the metabolism and utilization of essential fatty acids.

Variations in product color may occur.

Keep in a cool, dry place, tightly capped.

Rev. 009

Metadata

Product Details

UPC / SKU7 13947 74710 4
DSLD Entry Date2019-02-25
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
BrandAllergy Research Group
DSLD ID184081
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.