Metabolic Co-Factor
99/100
This product looks safe
- Niacin: 210mg is 6.0× the Tolerable Upper Intake Level (35mg)
- 71% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 210mg is 6.0× the Tolerable Upper Intake Level (35mg)
Label Data
6 Capsule(s)
Serving Size
30
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
71%
Evidence Coverage
Supplement Facts — Evidence Check
Vitamin A
2500 IU
(50% DV)
Vitamin C
384 mg
(640% DV)
800 IU
(200% DV)
✅ 1.3× RDA — within safe limits
📚 604 studies (Tier A: 16, B: 251)
100 IU
(333% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg)
📚 177 studies (Tier A: 3, B: 90)
20 mg
(1330% DV)
📊 16.7× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
20 mg
(1180% DV)
📊 15.4× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
210 mg
(1050% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 6.0× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
25 mg
(1250% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
400 mcg
(100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg)
📚 225 studies (Tier A: 10, B: 105)
500 mcg
(167% DV)
📊 16.7× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
200 mg
(2000% DV)
📊 40.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
250 mg
(63% DV)
📊 Market median: 4002.0mg (1 products)
📚 20 studies (Tier A: 0, B: 2)
30 mg
(200% DV)
✅ 2.7× RDA — within safe limits
📚 258 studies (Tier A: 6, B: 134)
200 mcg
(286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg)
📚 172 studies (Tier A: 0, B: 67)
0.5 mg
(25% DV)
✅ Within RDA (0.6× RDA of 0.9 mg)
📚 36 studies (Tier A: 0, B: 11)
10 mg
(500% DV)
📊 4.3× RDA — above typical dose (UL: 11 mg)
📚 8 studies — no high-quality reviews
1 mg
(833% DV)
📊 28.6× RDA — above typical dose
📚 197 studies (Tier A: 1, B: 55)
1 mg
(1330% DV)
📊 22.2× RDA — above typical dose (UL: 2 mg)
📚 2 studies — no high-quality reviews
2 mg
📊 Market median: 108.0mg (8 products)
📚 9 studies (Tier A: 0, B: 4)
200 mcg
📊 Market median: 0.5mg (6 products)
📚 1 studies (Tier A: 0, B: 1)
3 mg
📊 Market median: 3.0mg (58 products)
📚 2 studies — no high-quality reviews
Other Ingredients
Hydroxypropyl Methylcellulose
Microcrystalline Cellulose
L-Leucine
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (76% of products)
Nutrient (58% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Suggested Use As a dietary supplement, 6 capsules daily, or as directed by a healthcare practitioner.
⚠️ Warnings & Precautions
Taking more than 400 mcg of selenium per day from all sources should only be done under the guidance of a healthcare professional.
Not labeled for sale in California.
🧪 Formulation Notes
Now with Quatrefolic, the patented glucosamine salt of 5-methyltetrahydrofolate.
Additional Information
Metabolic Co-Factor is a multiple vitamin and mineral formula, developed by Dr. Leo Galland, M.D., to support the metabolism and utilization of essential fatty acids.
Variations in product color may occur.
Keep in a cool, dry place, tightly capped.
Rev. 009
Product Details
UPC / SKU
7 13947 74710 4
DSLD Entry Date
2019-02-25
Product Type
Multi-Vitamin and Mineral (MVM)
Form
Capsule
Brand
Allergy Research Group
DSLD ID
184081
Data Updated
2026-04-11
Research Evidence
337
Research Sources
54
Avg Quality Score
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A
Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
A
Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
A
Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
A
Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
A
Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
A
Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
A
Food fortification with multiple micronutrients: impact on health outcomes in general population
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