Home/ Supplements/ Vitamin A/ Natural Changes

Natural Changes

product on market Other (e.g. tea bag) Nature's Sunshine Safety: 98/100
98/100

This product looks safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 206mg is 206.0× the Tolerable Upper Intake Level (1.0mg)
  • 48% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins including A, C, D3, and B-complex vitamins, which support immune function and cellular metabolism. There is strong research evidence supporting the roles of these nutrients in maintaining general health. The formulation maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)

Folate: 206mg is 206.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Natural Changes
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Packet(s)
Serving Size
42
Servings
Other Combinations
Product Type
48%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
37.5 mcg (4% DV)
Vitamin C
437.5 mg (486% DV)
1.25 mcg (6% DV)
Within RDA (0.1× RDA) 608 studies (A:16, B:251)
20 mg (1061% DV)
16.7× RDA — above typical dose 76 studies (A:0, B:33)
20 mg (1538% DV)
15.4× RDA — above typical dose 13 studies (A:0, B:1)
40 mg (250% DV)
Exceeds UL by 1.1× (UL: 35 mg) 196 studies (A:5, B:63)
21.25 mg (1250% DV)
16.3× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
206 mcg DFE (52% DV)
Exceeds UL by 206.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
41.5 mcg (1729% DV)
17.3× RDA — above typical dose 139 studies (A:1, B:44)
100 mcg (333% DV)
3.3× RDA — above typical dose 27 studies (A:0, B:11)
80 mg (1000% DV)
16.0× RDA — above typical dose 2 studies — no high-quality reviews
13 mg (2% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
Calcium
150 mg (12% DV)
Iron
6.75 mg (4% DV)
47 mg (4% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
150 mg (30% DV)
Within RDA (0.4× RDA) 316 studies (A:8, B:159)
3.75 mg (34% DV)
Within RDA (0.3× RDA) 263 studies (A:6, B:134)
0.5 mg (56% DV)
Within RDA (0.6× RDA) 37 studies (A:0, B:11)
6.25 mg (11% DV)
2.7× RDA — within safe limits 9 studies — no high-quality reviews
Potassium
25 mg (1% DV)
0.25 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
C-X Proprietary Blend
840 mg
Wild Yam & Chaste Tree Proprietary Blend
210 mg
Super GLA Proprietary Blend
1080 mg
Gamma-Linolenic Acid
130 mg
Skeletal Strength Proprietary Blend
54 mg
Nutri-Calm Proprietary Blend
140 mg

Other Ingredients

Gelatin Glycerin Water Carob fruit extract Caramel color Gelatin Water Cellulose Stearic Acid Silicon Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended use: Take the contents of one Natural Changes packet with breakfast, and one with your evening meal. Follow this pattern for 21 days.

Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

This carton was sealed for your protection. Do not use if seal is missing or damaged.

Formulation Notes

Nature's Sunshine uses natural source materials that are subject to color variation.

C-X Provides herbal support for the female reproductive system. Wild Yam & Chaste Tree Historically used by women during menopause. Super GLA Provides essential Omega 6 fatty acids, which support the female reproductive system. Skeletal Strength & Nutri-Calm Helps maintain structural and neurological health.

Menopause & glandular system support 21 day program

Natural Changes support During menopause, the body requires more of certain nutrients than during other times in life. Natural Changes assists Mother Nature in providing these necessary nutrients. Natural Changes helps replenish the body's supply of vital nutrients used by the female glandular system.

Contents Natural Changes Packet 2 C-X capsules 1 Wild Yam & Chaste Tree capsule 1 Super GLA capsule 1 Skeletal Strength tablet 1 Nutri-Calm tablet

Additional Information

Please recycle this carton. We are committed to you and our planet. See QR code to learn more.

Herbal experts since 1972 New look! Same great product

Guaranteed Pure

Metadata

Product Details

DSLD Entry Date2025-09-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandNature's Sunshine
DSLD ID334374
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
Compare

Similar Products

Select-OB
Everett Laboratories · Other (e.g. tea bag)
100
Select-OB+DHA
Everett Laboratories · Other (e.g. tea bag)
100
Select-OB Berry Flavored Caplet
Exeltis USA · Other (e.g. tea bag)
100
Day 3 NeoLife Detox
NeoLife Nutritionals · Other (e.g. tea bag)
100
Advanced Diabetic Multivitamin Formula
Windmill Rx Premium Vitamins · Other (e.g. tea bag)
100
View all Vitamin A products →
Vitamin A research Best Vitamin A All Vitamin A products More from Nature's Sunshine View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.