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Hair, Skin & Nails

product on market Capsule Nature's Bounty Optimal Solutions Safety: 99/100
99/100

This product looks safe

  • Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains vitamins A, C, D, E, and thiamine, which are supported by strong evidence for maintaining skin integrity and cellular health. These nutrients act as antioxidants and essential cofactors for collagen synthesis and tissue repair. The overall ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Hair, Skin & Nails
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Caplet(s)
Serving Size
20
Servings
Other Combinations
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1500 mcg (167% DV)
Vitamin C
60 mg (67% DV)
25 mcg (125% DV)
1.7× RDA — within safe limits 608 studies (A:16, B:251)
6.7 mg (45% DV)
Within RDA (0.4× RDA) 179 studies (A:3, B:90)
5 mg (417% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
2 mg (154% DV)
1.5× RDA — within safe limits 13 studies (A:0, B:1)
25 mg (156% DV)
1.8× RDA — within safe limits 196 studies (A:5, B:63)
5 mg (294% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
333 mcg DFE (83% DV)
Exceeds UL by 333.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
8 mcg (333% DV)
3.3× RDA — above typical dose 139 studies (A:1, B:44)
3000 mcg (10000% DV)
100.0× RDA — above typical dose 27 studies (A:0, B:11)
15 mg (300% DV)
3.0× RDA — within safe limits 2 studies — no high-quality reviews
Calcium
200 mg (15% DV)
87 mg (7% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
50 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
7.5 mg (68% DV)
Within RDA (0.7× RDA) 263 studies (A:6, B:134)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
30 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (19 products)
Horsetail, Powder
3 mg
50 mg
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)

Other Ingredients

Cellulose Carnauba Wax Choline Bitartrate Gelatin Mannitol Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take three (3) caplets daily, preferably with a meal.

Warnings & Precautions

Contains fish (cod, cusk, flounder, haddock, hake, pollock, redish, sole) ingredients.

Warning: If you are pregnant, nursing, taking any medications, planning any medical or surgical procedure, have any medical condition, or are planning to undergo any clinical lab testing, consult your doctor before use. Some supplements may interact with certain medications and/or interfere with certain lab tests.

It is advisable to consult your doctor before using biotin doses above 2,500 mcg per day. If any adverse reactions occur, stop use and consult your doctor. Do not use if seal under cap is broken or missing.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Formulation Notes

3,000 mcg Biotin per serving 16 key ingredients including antioxidants

No artificial color, flavor or sweetener, no sugar, no milk, no lactose, no gluten, no wheat, no shellfish. Sodium free.

Guaranteed quality Laboratory tested

No artificial flavors

Made in the USA with select ingredients from around the world.

Additional Information

#1 brand for hair, skin & nails Source: IRI Total US - Multi Outlet: Latest 52 weeks ending 05/23/21.

Store at room temperature.

Nutrition questions or comments? Call 1-800-433-2990 Sign up for news and offers at NaturesBounty.com

At Nature's Bounty, we believe health and beauty go hand in hand. With nearly 50 years of making quality vitamins and more than 20 years in the beauty business, you can trust that every Nature's Bounty product is backed by science and made with the purest ingredients...guaranteed.

Metadata

Product Details

DSLD Entry Date2024-05-23
Product TypeOther Combinations
FormCapsule
BrandNature's Bounty Optimal Solutions
DSLD ID308219
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.