Hair, Skin & Nails by Nature's Bounty Optimal Solutions — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
64% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

3 Caplet(s) Serving Size

20 Servings

Other Combinations Product Type

64% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1500 mcg (167% DV)

Vitamin C

60 mg (67% DV)

Vitamin D

25 mcg (125% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

6.7 mg (45% DV)

✅ Within RDA (0.4× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 6.7mg UL 1000mg

Thiamine

5 mg (417% DV)

📊 4.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 5mg

Riboflavin

2 mg (154% DV)

✅ 1.5× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 2mg

Niacin

25 mg (156% DV)

✅ 1.8× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 25mg UL 35mg

Vitamin B6

5 mg (294% DV)

📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 5mg UL 100mg

Folate

333 mcg DFE (83% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 333.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 333mg UL 1.0mg

Vitamin B12

8 mcg (333% DV)

📊 3.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.008mg

Biotin

3000 mcg (10000% DV)

📊 100.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 3.0mg

Pantothenic Acid

15 mg (300% DV)

✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 15mg

Calcium

200 mg (15% DV)

Phosphorus

87 mg (7% DV)

✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 87mg UL 4000mg

Magnesium

50 mg (12% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 50mg

Zinc

7.5 mg (68% DV)

✅ Within RDA (0.7× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 7.5mg UL 40mg

Manganese

2 mg (87% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Para-Aminobenzoic Acid

10 mg

📊 Market median: 500.0mg (9 products)

This product: 10mg

Inositol

30 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 30mg

Citrus Bioflavonoid / Rutin Complex

38 mg

📊 Market median: 500.0mg (19 products)

This product: 38mg

Horsetail, Powder

3 mg

Collagen

50 mg

📊 Market median: 20.0mg (931 products) 📚 233 studies (Tier A: 1, B: 90)

This product: 50mg

Other Ingredients

Cellulose Carnauba Wax Choline Bitartrate Gelatin Mannitol Silica Magnesium Stearate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take three (3) caplets daily, preferably with a meal.

⚠️ Warnings & Precautions

Contains fish (cod, cusk, flounder, haddock, hake, pollock, redish, sole) ingredients.

Warning: If you are pregnant, nursing, taking any medications, planning any medical or surgical procedure, have any medical condition, or are planning to undergo any clinical lab testing, consult your doctor before use. Some supplements may interact with certain medications and/or interfere with certain lab tests.

It is advisable to consult your doctor before using biotin doses above 2,500 mcg per day. If any adverse reactions occur, stop use and consult your doctor. Do not use if seal under cap is broken or missing.

Not intended for use by persons under the age of 18. Keep out of reach of children.

🧪 Formulation Notes

3,000 mcg Biotin per serving 16 key ingredients including antioxidants

No artificial color, flavor or sweetener, no sugar, no milk, no lactose, no gluten, no wheat, no shellfish. Sodium free.

Guaranteed quality Laboratory tested

No artificial flavors

Made in the USA with select ingredients from around the world.

Additional Information

#1 brand for hair, skin & nails Source: IRI Total US - Multi Outlet: Latest 52 weeks ending 05/23/21.

Store at room temperature.

Nutrition questions or comments? Call 1-800-433-2990 Sign up for news and offers at NaturesBounty.com

At Nature's Bounty, we believe health and beauty go hand in hand. With nearly 50 years of making quality vitamins and more than 20 years in the beauty business, you can trust that every Nature's Bounty product is backed by science and made with the purest ingredients...guaranteed.

Product Details

DSLD Entry Date 2024-05-23

Product Type Other Combinations

Form Capsule

Brand Nature's Bounty Optimal Solutions

DSLD ID 308219

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →