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Mega-Stress Sustained Release

product on market Tablet or Pill NaturesPlus Safety: 96/100
96/100

This product looks safe

  • Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 76% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins and Vitamin C, which are supported by strong evidence for supporting energy metabolism and immune function. These nutrients play essential roles in cellular processes and stress response. The ingredient profile maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Mega-Stress Sustained Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
76%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (556% DV)
60 mg (5000% DV)
50.0× RDA — above typical dose 76 studies (A:0, B:33)
60 mg (4615% DV)
46.2× RDA — above typical dose 13 studies (A:0, B:1)
125 mg NE (781% DV)
Exceeds UL by 3.6× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5882% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
75 mcg (250% DV)
2.5× RDA — within safe limits 27 studies (A:0, B:11)
200 mg (4000% DV)
40.0× RDA — above typical dose 2 studies — no high-quality reviews
32 mg (6% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Calcium
100 mg (8% DV)
50 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
25 mg (227% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
50 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
25 mg
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)

Other Ingredients

Calcium Carbonate Microcrystalline Cellulose Dicalcium Phosphate Stearic Acid Magnesium Oxide Zinc Sulfate Magnesium Stearate Hydroxypropyl Methylcellulose Silica Rose Hip isolated Soy Protein Rice Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: One tablet daily.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Free from artificial colors and artificial preservatives. Free from the allergens milk, eggs, fish, crustacean shellfish, tree nuts, peanuts and wheat.

Vegetarian

Gluten free

In a special base which provides for the gradual release of ingredients over a prolonged period of time. Micro-Gel sustained release system

B-complex, vitamin C & herbs

Stress support

Additional Information

Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU0 97467 01260 8
DSLD Entry Date2024-04-23
Product TypeOther Combinations
FormTablet or Pill
BrandNaturesPlus
DSLD ID304649
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.