PureResponse Multivitamin by Pure Encapsulations — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Vitamin D: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)
62% of ingredients have research evidence

C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains essential vitamins A, C, D, E, and K, which are supported by strong evidence for maintaining immune function and bone health. These nutrients play critical roles in cellular protection and coagulation. The overall safety profile is high, though evidence coverage for this specific blend is limited.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

⚠️ Vitamin D: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)

Label Data

2 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

62% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1500 mcg (167% DV)

Vitamin C

100 mg (111% DV)

Vitamin D

125 mcg (625% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.2× (UL: 0.1 mg) 📚 608 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.125mg UL 0.1mg

Vitamin E

15 mg (100% DV)

✅ Within RDA (1.0× RDA of 15 mg) 📚 179 studies (Tier A: 3, B: 90)

RDA 15mg This product: 15mg UL 1000mg

Vitamin K

135 mcg (113% DV)

✅ 1.1× RDA — within safe limits 📚 275 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.135mg

Thiamine

5 mg (417% DV)

📊 4.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 5mg

Riboflavin

5 mg (385% DV)

📊 3.8× RDA — above typical dose 📚 13 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 5mg

Niacin

20 mg (125% DV)

✅ 1.4× RDA — within safe limits 📚 196 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

10.4 mg (612% DV)

📊 8.0× RDA — above typical dose (UL: 100 mg) 📚 114 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 10.4mg UL 100mg

Metafolin

667 mcg DFE (167% DV)

Vitamin B12

1000 mcg (41667% DV)

📊 416.7× RDA — above typical dose 📚 139 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 1.0mg

Biotin

300 mcg (1000% DV)

📊 10.0× RDA — above typical dose 📚 27 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

50 mg (1000% DV)

📊 10.0× RDA — above typical dose 📚 2 studies — no high-quality reviews

RDA 5mg This product: 50mg

Choline

20 mg (4% DV)

📊 Market median: 125.0mg (294 products) 📚 38 studies (Tier A: 1, B: 7)

RDA 550mg This product: 20mg UL 3500mg

Magnesium

100 mg (24% DV)

✅ Within RDA (0.2× RDA of 420 mg) 📚 316 studies (Tier A: 8, B: 159)

RDA 420mg This product: 100mg UL 350mg

Zinc

25 mg (227% DV)

✅ 2.3× RDA — within safe limits 📚 263 studies (Tier A: 6, B: 134)

RDA 11mg This product: 25mg UL 40mg

Selenium

150 mcg (273% DV)

✅ 2.7× RDA — within safe limits 📚 173 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.15mg UL 0.4mg

Chromium

200 mcg (571% DV)

📊 5.7× RDA — above typical dose 📚 199 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.2mg

Molybdenum

150 mcg (333% DV)

📊 3.3× RDA — above typical dose (UL: 2 mg) 📚 3 studies — no high-quality reviews

RDA 0.045mg This product: 0.15mg UL 2mg

Potassium

15 mg (1% DV)

Vitamin K2

45 mcg

✅ Within RDA (0.4× RDA of 0.12 mg) 📚 275 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.045mg

Mixed Tocopherols

20 mg

✅ 1.3× RDA — within safe limits 📚 179 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20mg UL 1000mg

FloraGlo

3 mg

Zeaxanthin

500 mcg

📊 Market median: 4.0mg (32 products)

This product: 0.5mg

Eleuthero Root Extract

125 mg

Reishi Fruiting Body Extract

75 mg

📊 Market median: 340.0mg (243 products) 📚 3 studies — no high-quality reviews

This product: 75mg

Other Ingredients

Cellulose Water Ascorbyl Palmitate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 2 capsules daily, with a meal.

⚠️ Warnings & Precautions

Warning: Vitamin K may be contraindicated with Coumadin (Warfarin). If you are pregnant or lactating, have any health condition or are taking any medication, particularly blood thinning medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

🧪 Formulation Notes

Certified Gluten-Free by the Gluten-Free Certified Organization www.gluten.org Gluten-Free, Non-GMO & Hypoallergenic

Gluten-Free, Non-GMO & Hypoallergenic

Multivitamin/mineral complex designed to support immune balance and responsiveness

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

GFCO.org (Gluten-Free Certification Organization)

Product Details

UPC / SKU 7 66298 02218 5

DSLD Entry Date 2023-12-14

Product Type Other Combinations

Form Capsule

Brand Pure Encapsulations

DSLD ID 299738

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →