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Proactive 65+ for Men & Women

product on market Tablet or Pill Bayer One A Day Safety: 98/100
98/100

This product looks safe

  • Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
  • 70% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains vitamins A, C, D, K, and thiamine, which support immune function, bone health, and cellular energy metabolism. There is strong evidence supporting the general roles of these micronutrients in maintaining systemic health. However, the overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Proactive 65+ for Men & Women
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
75
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
70%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
670 mcg (74% DV)
Vitamin C
90 mg (100% DV)
30 mcg (150% DV)
2.0× RDA — within safe limits 608 studies (A:16, B:251)
1.2 mg (100% DV)
Within RDA (1.0× RDA) 76 studies (A:0, B:33)
1.7 mg (131% DV)
1.3× RDA — within safe limits 13 studies (A:0, B:1)
20 mg (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
2 mg (118% DV)
1.5× RDA — within safe limits 114 studies (A:3, B:35)
665 mcg DFE (166% DV)
Exceeds UL by 665.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
50 mcg (2083% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
30 mcg (100% DV)
Within RDA (1.0× RDA) 27 studies (A:0, B:11)
10 mg (200% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews
Calcium
500 mg (38% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (24% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
55 mcg (100% DV)
Within RDA (1.0× RDA) 173 studies (A:0, B:67)
1 mg (111% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
24 mcg (69% DV)
Within RDA (0.7× RDA) 199 studies (A:1, B:55)

Other Ingredients

Calcium Carbonate Magnesium Oxide Microcrystalline Cellulose Ascorbic Acid Maltodextrin Croscarmellose Sodium Beta Carotene Biotin Cholecalciferol Chromium Chloride Copper Sulfate Cyanocobalamin D-Calcium Pantothenate FD&C Yellow #6 Aluminum Lake Folic Acid Gelatin Hydroxypropyl Methylcellulose Manganese Sulfate Mica Niacinamide Polyethylene Glycol Potassium Iodide Pyridoxine Hydrochloride Riboflavin Silicon Dioxide Sodium Selenite Stearic Acid Thiamine Mononitrate Titanium Dioxide Vitamin A Acetate Zinc Oxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults: Two tablets daily, with food.

Warnings & Precautions

Not a replacement for heart medications.

For adult use only.

Not for children. Keep out of reach of children

If pregnant, breast-feeding, taking medication, or have any medical condition ask a health professional before use.

Do not exceed recommended intake Do not use this product if printed safety seal bearing "Bayer HealthCare" under cap is torn or missing.

Formulation Notes

Only complete multivitamin specially formulated for this age: Excellent source of vitamin D - which is harder to get from the sun as you age High potency vitamin B12 - which at this age is easier to absorb from a supplement or fortified food, than what is found naturally in food

Formulated without vitamin K for those who have been instructed by their physician to avoid this vitamin

Formulated to support: Healthy blood pressure with vitamin C, calcium, magnesium and vitamin D Bone health with calcium, magnesium and vitamin D Physical energy with B-vitamins to help convert food to fuel Cell health with antioxidants: vitamins A, C, zinc, manganese, copper and selenium Heart health with vitamins B6, B12 and folic acid

50% smaller than One A Day Women's 50+ Healthy Advantage To help support blood pressure levels already within normal range.

One A Day Proactive 65+ is the only complete multivitamin specially formulated for men and women 65+ with key nutrients important for this age.

Formulated with: Excellent source of vitamin D High potency vitamin B12 And other key nutrients

Free of: Artificial sweeteners and artificial flavors and dairy (milk) and wheat allergens

Easy to swallow mini tablets

Does not contain vitamin K

No artificial sweeteners or flavors

Additional Information

Among the leading brands

Store at room temperature. Avoid excessive heat above 40 degrees C (104 degrees F).

Questions or comments? Please call 1-800-800-4793 (Mon-Fri 9am - 5pm EST)

Metadata

Product Details

UPC / SKU0 16500 56164 4
DSLD Entry Date2022-06-16
Product TypeMulti-Vitamin and Mineral (MVM)
FormTablet or Pill
BrandBayer One A Day
DSLD ID269938
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.