Chewable Multi-Vitamin & Minerals Jungle Berry by Natural Factors Big Friends — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Folate: 85mg is 85.0× the Tolerable Upper Intake Level (1.0mg)
58% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 85mg is 85.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

Other Combinations Product Type

58% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 Calorie(s)

Total Carbohydrates

1 Gram(s) (1% DV)

Xylitol

1 Gram(s)

Vitamin A

300 mcg (100% DV)

Vitamin C

100 mg (667% DV)

Vitamin D3

5 mcg (33% DV)

✅ Within RDA (0.3× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.005mg UL 0.1mg

Vitamin E

8 mg (140% DV)

✅ Within RDA (0.5× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 8mg UL 1000mg

Vitamin K2

2.5 mcg (8% DV)

📊 Market median: 0.1mg (347 products) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.0025mg

Thiamine

2.5 mg (500% DV)

✅ 2.1× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 2.5mg

Riboflavin

2.5 mg (500% DV)

✅ 1.9× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 2.5mg

Niacin

2.5 mg (42% DV)

✅ Within RDA (0.2× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 2.5mg UL 35mg

Vitamin B6

2.5 mg (500% DV)

✅ 1.9× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2.5mg UL 100mg

Folate

85 mcg DFE (57% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 85.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 85mg UL 1.0mg

Vitamin B12

5 mcg (556% DV)

✅ 2.1× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.005mg

Biotin

5 mcg (63% DV)

✅ Within RDA (0.2× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.005mg

Pantothenic Acid

5 mg (250% DV)

✅ Within RDA (1.0× RDA of 5 mg) 📚 1 studies — no high-quality reviews

RDA 5mg This product: 5mg

Choline

2.5 mg (1% DV)

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 2.5mg UL 3500mg

Calcium

65 mg (9% DV)

Iron

2.5 mg (36% DV)

Magnesium

32.5 mg (41% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 32.5mg

Zinc

1.5 mg (50% DV)

✅ Within RDA (0.1× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 1.5mg UL 40mg

Copper

0.125 mg (42% DV)

✅ Within RDA (0.1× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.125mg UL 10mg

Sodium

10 mg (1% DV)

Whole Food Concentrates

10 mg

Stevia leaf powder

2 mg

Inositol

2.5 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 2.5mg

Other Ingredients

Microcrystalline Cellulose natural Fruit flavors modified Food Starch Citric Acid Magnesium Stearate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Children 4 or More Years of Age Vegetarian Gluten Free Dairy Free Sugar Free Children more than 1 but less than 4

Product Information

📋 Directions for Use

Suggested Usage: Children 3 years & older: Chew 1 tablet 1-2 times per day with food or as directed by a health professional.

⚠️ Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Sealed for your protection. Do not use if seal is broken.

Contains soy.

🧪 Formulation Notes

Big Friends Chewable Multi-Vitamin is a comprehensive and delicious chewable multivitamin and mineral formula - sweetened by xylitol, a healthy sugar-free alternative for children that does not harm their teeth.

Formulated to support the good health of active and growing children ages 3 and up.

Helps in the development and maintenance of healthy bones, teeth, gums, eyesight, night vision, healthy skin, membranes, and immune function. Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, egg, fish, shellfish, tree nuts, or GMOs.

Suitable for vegetarians.

With whole food concentrates

Sugar & gluten free

Naturally sourced flavors & colors

Not a significant source of sugar

Additional Information

isura Non-GMO - Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place.

Product of Canada Recyclable container and label.

Purity & Potency Guaranteed

Product Details

UPC / SKU 0 68958 01549 1

DSLD Entry Date 2020-05-22

Product Type Other Combinations

Form Tablet or Pill

Brand Natural Factors Big Friends

DSLD ID 220347

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →