🟢 99/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 65% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
450 mcg RAE (50% DV)
Vitamin C
250 mg (278% DV)
99 mg (660% DV)
📊 6.6× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 99mg UL 1000mg
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
25 mg (1923% DV)
📊 19.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 25mg
100 mg (625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg
25 mg (1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
500 mcg (1667% DV)
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg
150 mg (3000% DV)
📊 30.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 150mg
200 mg (48% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 200mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
150 mcg (273% DV)
✅ 2.7× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.15mg UL 0.4mg
4 mg (174% DV)
✅ 1.7× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 4mg UL 11mg
150 mcg (429% DV)
📊 4.3× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.15mg
75 mcg (167% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
Potassium
99 mg (2% DV)
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 150mg
📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)
This product: 150mg
📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)
This product: 150mg
50 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 50mg UL 1200mg
Shilajit extract
50 mg
✅ Within RDA (0.6× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 9mg UL 1000mg
750 mcg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 0.75mg UL 20mg

Other Ingredients

HPMC Ascorbyl Palmitate Medium-Chain Triglyceride Oil L-Leucine Silica

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Suggested Use: Take 4 capsules daily with food or use as directed by your healthcare professional. California residents should not exceed 2 capsules daily. May be taken in divided doses if desired. Do not take within 5 hours of bedtime as it may interfere with sleep.

⚠️ Warnings & Precautions

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Do not use if tamper seal is damaged.

Storage: Keep closed in a cool, dry place out of reach by children.

Servings Per Container: 30 (California Residents: 60)

🧪 Formulation Notes

Optimal Start is a unique multivitamin free of copper, iron, calcium, B12 and folate – providing a tailored starting point for those who may be sensitive to methylation support supplements. Additional adaptogenic herbs may also help support healthy glandular function.

Does Not Contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, artificial flavors, or artificial colors.

Additional Information

Storage: Keep closed in a cool, dry place out of reach by children.

Optimal Start Meets or Exceeds cGMP Quality Standards.

This package is completely recyclable

Physician Formulated

Product Details

UPC / SKU 7 98295 54929 7
DSLD Entry Date 2020-01-25
Product Type Other Combinations
Form Capsule
DSLD ID 211058
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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