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Optimal Start

product on market Capsule Seeking Health Safety: 99/100
99/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 65% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains essential vitamins A, C, E, and B-complex, which are supported by strong evidence for maintaining immune function and cellular energy metabolism. These nutrients act as antioxidants and cofactors in critical biochemical pathways. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Optimal Start
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
65%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
450 mcg RAE (50% DV)
Vitamin C
250 mg (278% DV)
99 mg (660% DV)
6.6× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
25 mg (1923% DV)
19.2× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
500 mcg (1667% DV)
16.7× RDA — above typical dose 27 studies (A:0, B:11)
150 mg (3000% DV)
30.0× RDA — above typical dose 2 studies — no high-quality reviews
200 mg (48% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
150 mcg (273% DV)
2.7× RDA — within safe limits 173 studies (A:0, B:67)
4 mg (174% DV)
1.7× RDA — within safe limits 9 studies — no high-quality reviews
150 mcg (429% DV)
4.3× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (167% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Potassium
99 mg (2% DV)
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)
50 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)
Shilajit extract
50 mg
Within RDA (0.6× RDA) 179 studies (A:3, B:90)
750 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

HPMC Ascorbyl Palmitate Medium-Chain Triglyceride Oil L-Leucine Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take 4 capsules daily with food or use as directed by your healthcare professional. California residents should not exceed 2 capsules daily. May be taken in divided doses if desired. Do not take within 5 hours of bedtime as it may interfere with sleep.

Warnings & Precautions

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Do not use if tamper seal is damaged.

Storage: Keep closed in a cool, dry place out of reach by children.

Servings Per Container: 30 (California Residents: 60)

Formulation Notes

Optimal Start is a unique multivitamin free of copper, iron, calcium, B12 and folate – providing a tailored starting point for those who may be sensitive to methylation support supplements. Additional adaptogenic herbs may also help support healthy glandular function.

Does Not Contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, artificial flavors, or artificial colors.

Additional Information

Storage: Keep closed in a cool, dry place out of reach by children.

Optimal Start Meets or Exceeds cGMP Quality Standards.

This package is completely recyclable

Physician Formulated

Metadata

Product Details

UPC / SKU7 98295 54929 7
DSLD Entry Date2020-01-25
Product TypeOther Combinations
FormCapsule
DSLD ID211058
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.