Centrum Multi + Probiotics Adults 50+ by Centrum — Ingredients, Evidence & Safety

🟢 98/100

This product looks safe

Folate: 260mg is 260.0× the Tolerable Upper Intake Level (1.0mg)
74% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 260mg is 260.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

Other Combinations Product Type

74% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

450 mcg (50% DV)

Vitamin C

90 mg (100% DV)

Vitamin D3

25 mcg (125% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

10.8 mg (72% DV)

✅ Within RDA (0.7× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 10.8mg UL 1000mg

Thiamine

0.8 mg (67% DV)

✅ Within RDA (0.7× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 0.8mg

Riboflavin

1.3 mg (100% DV)

✅ Within RDA (1.0× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 1.3mg

Niacin

14.4 mg (90% DV)

✅ Within RDA (1.0× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 14.4mg UL 35mg

Vitamin B6

1 mg (59% DV)

✅ Within RDA (0.8× RDA of 1.3 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 1mg UL 100mg

Folate

260 mcg DFE (65% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 260.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 260mg UL 1.0mg

Vitamin B12

6 mcg (250% DV)

✅ 2.5× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.006mg

Biotin

45 mcg (150% DV)

✅ 1.5× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.045mg

Pantothenic Acid

5.4 mg (108% DV)

✅ 1.1× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 5.4mg

Iodine

135 mcg (90% DV)

✅ Within RDA (0.9× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.135mg UL 1.1mg

Zinc

9 mg (82% DV)

✅ Within RDA (0.8× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 9mg UL 40mg

Selenium

11 mcg (20% DV)

✅ Within RDA (0.2× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.011mg UL 0.4mg

Copper

0.5 mg (56% DV)

✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.5mg UL 10mg

Manganese

1.8 mg (78% DV)

✅ Within RDA (0.8× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 1.8mg UL 11mg

Chromium

36 mcg (103% DV)

✅ Within RDA (1.0× RDA of 0.035 mg) 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.036mg

Bifidobacterium animalis

Other Ingredients

Microcrystalline Cellulose Ascorbic Acid Maltodextrin Dibasic Calcium Phosphate DL-Alpha-Tocopheryl Acetate Modified Corn Starch Niacinamide Mono- and Di-Glycerides Zinc Oxide Contains Less Than 2% of

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (91% of products) Nutrient (14% of products)

Target Groups

Seniors/Mature (>50 Years)

Product Information

📋 Directions for Use

Suggested Use: Adults: Take one (1) tablet daily. Do not exceed suggested use. Not formulated for use in children.

⚠️ Warnings & Precautions

As with any supplement, if you are pregnant, nursing, or taking medication, consult your doctor before use.

If taking other supplements, read label, since supplements may contain the same ingredient.

Keep out of reach of children.

Do not use if break-away tab is broken or missing.

Do not exceed suggested use.

Not formulated for use in children.

Additional Information

Store at room temperature (not above 25(0)C/77(0)F). Protect from moisture.

Questions? Comments? Call 1-877-CENTRUM (236-8786)

PAA098020

Advanced Support for Whole Body Benefits and Immune Function+Digestive Benefits

Made in Italy

For most recent product information, visit www.centrum.com

1424188

Product Details

DSLD Entry Date 2019-04-25

Product Type Other Combinations

Form Tablet or Pill

Brand Centrum

DSLD ID 200928

Data Updated 2026-04-11

Research Evidence

691 Research Sources

52 Avg Quality Score

255 Clinical Trial

205 Meta Analysis

123 Rct

81 Systematic Review

18 Cochrane Review

2 Guideline

2 Regulatory Source

1 Other

1 Narrative Review

1 Openfda Safety

A Probiotics for preventing acute upper respiratory tract infections

Systematic Review The Cochrane database of systematic reviews 2022

PubMed DOI Cochrane

A Probiotics for preventing acute upper respiratory tract infections

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

A Probiotics for maintenance of remission in ulcerative colitis

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Probiotics for induction of remission in ulcerative colitis

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Probiotics for preventing acute upper respiratory tract infections

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Probiotics for treating eczema

Meta Analysis The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Probiotics for treating acute infectious diarrhoea

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies

Systematic Review International journal of molecular sciences 2022

PubMed DOI

A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Probiotics to prevent infantile colic

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

View all evidence for Probiotics →