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Co-Enzyme B-Complex With Alpha Lipoic Acid and CoQ10

product on market Tablet or Pill NOW Safety: 98/100
98/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains B-vitamins and Vitamin C, which are supported by strong evidence for their roles in energy metabolism and cellular function. These ingredients facilitate the conversion of nutrients into fuel and support antioxidant defenses. Research indicates a high safety profile for these components when taken within recommended daily limits.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Co-Enzyme B-Complex With Alpha Lipoic Acid and CoQ10
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
60 mg (100% DV)
50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (500% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
250 mcg (4167% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
50 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
25 mg
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
25 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
30 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
400 mcg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)

Other Ingredients

Cellulose Silica Magnesium Stearate Croscarmellose Sodium Enteric Coating
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 2 tablets daily with food.

Warnings & Precautions

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do Not Eat Freshness Packet. Keep in Bottle.

Formulation Notes

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Vegetarian/Vegan

NOW(R) Co-Enzyme B-Complex contains B Vitamins in their active or "Co-enzyme" forms and the tablets are enteric coated to deliver them to intestinal absorption sites intact, unharmed by stomach acids.

Additional Information

Natural color variation may occur in this product. Please Recycle.

CODE 0405 V7

Nutritional Health

~ Supports Healthy Nervous System* ~ Superior Utilization

Enteric coated

Vitamins

Family owned since 1968.

GMP Quality Assured

B-Complex Vitamins are needed by the body for energy production, synthesis of blood cells, healthy nervous system function, and countless other metabolic processes.* The forms of the B Vitamins found in foods and most supplements however, are not readily utilized by the body and require conversion into their active forms before they can perform their functions as co-factors in biochemical reactions.*

Metadata

Product Details

UPC / SKU7 33739 00405 5
DSLD Entry Date2015-08-25
Product TypeOther Combinations
FormTablet or Pill
BrandNOW
DSLD ID49544
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
52
Avg Quality
13
Rct
4
Meta Analysis
2
Systematic Review
2
Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024 PubMed DOI
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 PubMed DOI
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023 PubMed DOI
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018 PubMed DOI
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012 PubMed DOI
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020 PubMed DOI
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024 PubMed DOI
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024 PubMed DOI
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.