🟢 98/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
60 mg (100% DV)
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
100 mg (500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg
50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
250 mcg (4167% DV)
📊 104.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.25mg
300 mcg (100% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (500% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
50 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 50mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 50mg
25 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 25mg UL 3500mg
25 mg
📊 Market median: 500.0mg (9 products)
This product: 25mg
30 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 30mg
400 mcg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 0.4mg UL 1200mg

Other Ingredients

Cellulose Silica Magnesium Stearate Croscarmellose Sodium Enteric Coating

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (87% of products) Nutrient (16% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 2 tablets daily with food.

⚠️ Warnings & Precautions

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do Not Eat Freshness Packet. Keep in Bottle.

🧪 Formulation Notes

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Vegetarian/Vegan

NOW(R) Co-Enzyme B-Complex contains B Vitamins in their active or "Co-enzyme" forms and the tablets are enteric coated to deliver them to intestinal absorption sites intact, unharmed by stomach acids.

Additional Information

Natural color variation may occur in this product. Please Recycle.

CODE 0405 V7

Nutritional Health

~ Supports Healthy Nervous System* ~ Superior Utilization

Enteric coated

Vitamins

Family owned since 1968.

GMP Quality Assured

B-Complex Vitamins are needed by the body for energy production, synthesis of blood cells, healthy nervous system function, and countless other metabolic processes.* The forms of the B Vitamins found in foods and most supplements however, are not readily utilized by the body and require conversion into their active forms before they can perform their functions as co-factors in biochemical reactions.*

Product Details

UPC / SKU 7 33739 00405 5
DSLD Entry Date 2015-08-25
Product Type Other Combinations
Form Tablet or Pill
Brand NOW
DSLD ID 49544
Data Updated 2026-04-11

Research Evidence

21 Research Sources
52 Avg Quality Score
13 Rct
4 Meta Analysis
2 Systematic Review
2 Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences
View all evidence for Alpha Lipoic Acid →

Compare Similar Products

View all Alpha Lipoic Acid products →