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Active Lipoic Acid 300 mg

product on market Tablet or Pill Country Life Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Alpha-lipoic acid and biotin are supported by moderate evidence for metabolic support and nerve function. Calcium and phosphorus provide essential mineral support for bone health. Overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Active Lipoic Acid 300 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mcg (3333% DV)
33.3× RDA — above typical dose 27 studies (A:0, B:11)
Calcium
60 mg (5% DV)
31 mg (2% DV)
Market median: 99.0mg (503 products) 13 studies (A:0, B:3)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews

Other Ingredients

Cellulose Stearic Acid Cellulose & Glycerin Coating Silica Vegetable Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults take one (1) tablet daily with food or as directed by a health care professional.

Warnings & Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers.

Caution: Not for use by pregnant or nursing women. If you are diabetic or hypoglycemic, taking medication, planning a surgery, or have a medical condition, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of reach of children.

Formulation Notes

R-alpha lipoic acid is an antioxidant that protects against free radicals. It has been heat stabilized. This formula includes 30 mg alpha-lipoic acid 270 mg alpha-lipoic acid.

Yes certified gluten-free by GFCO.ORG

Yes Certified Vegan by the AVA

Yes Kosher

No Yeast, corn or wheat No Soy, milk or sugar No Preservatives No Artificial colors, flavors or sweeteners No Magnesium stearate

This product has been manufactured at a GMP registered facility.

Certified gluten-free

Heat stable R-Lipoic Acid

Protects against free radicals

Our pledge of integrity Authenticity, cleanliness, freshness, consistency, accuracy

Additional Information

Yes Recyclable packaging Yes Manufacturing supports wind power

Certified B Corporations GF Certified Gluten-free Kosher

Established 1971

Store in a dry place between 59 degrees-86 degrees F.

Metadata

Product Details

UPC / SKU0 15794 01651 9
DSLD Entry Date2020-07-23
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID230703
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
52
Avg Quality
13
Rct
4
Meta Analysis
2
Systematic Review
2
Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024 PubMed DOI
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 PubMed DOI
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023 PubMed DOI
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018 PubMed DOI
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012 PubMed DOI
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020 PubMed DOI
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024 PubMed DOI
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024 PubMed DOI
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences PubMed
View all evidence for Alpha Lipoic Acid →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.