Clinically Advanced Hair, Skin & Nails by NOW Solutions — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
57% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

3 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

57% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1500 mcg (167% DV)

Vitamin C

60 mg (67% DV)

Vitamin E

20 mg (133% DV)

✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20mg UL 1000mg

Thiamine

10 mg (833% DV)

📊 8.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 10mg

Riboflavin

10 mg (769% DV)

📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 10mg

Niacin

18 mg (113% DV)

✅ 1.3× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 18mg UL 35mg

Vitamin B6

2 mg (118% DV)

✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2mg UL 100mg

Folate

680 mcg DFE (170% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 680mg UL 1.0mg

Vitamin B12

100 mcg (4167% DV)

📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.1mg

Biotin

300 mcg (1000% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

14 mg (280% DV)

✅ 2.8× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 14mg

Choline

25 mg (5% DV)

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 25mg UL 3500mg

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Copper

2 mg (222% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Cynatine HNS

500 mg

Methylsulfonylmethane

500 mg

📊 Market median: 1000.0mg (2 products)

This product: 500mg

Beef Gelatin

200 mg

L-Proline

100 mg

Horsetail Aerial Parts Extract

100 mg

Hyaluronic Acid

50 mg

📊 Market median: 100.0mg (173 products)

Median 100.0mg This product: 50mg

Inositol

25 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 25mg

Other Ingredients

Hypromellose Ascorbyl Palmitate Silicon Dioxide Rice Flour Maltodextrin Food Starch, Modified Citric Acid Vitamin E

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Halal Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 3 capsules daily with food.

⚠️ Warnings & Precautions

Not manufactured with milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition (especially glaucoma).

Keep out of reach of children.

This product contains Biotin which may interfere with some blood test results. Go to nowfoods.com/biotinlab for details.

Vitamin E from non-GMO soy.

🧪 Formulation Notes

NOW Solutions Clinically Advanced Hair, Skin & Nails is formulated to nurture hair, skin, and nails from the inside. This product features Cynatine HNS a revolutionary patented and bioavailable form of solubilized Keratin that can help you maintain full, lustrous hair and nails that are strong and flexible. Cynatine HNS can also help the skin to retain its youthful moisture and elasticity, as well as battle signs of aging associated with free radicals. This product also has other critical nutrients necessary for the support and maintenance of the skin’s healthy and youthful appearance.

Not manufactured with milk, egg, fish, shellfish, tree nut or sesame ingredients.

Natural color variation may occur in this product.

Crescent H (Halal)

Clinically Advanced Hair, Skin & Nails with clinically tested Cynatine

Maintains healthy hair, skin and nails

Made and quality tested in the USA with globally sourced ingredients.

Additional Information

Store in a cool, dry place after opening.

This bottle is made from 100% PCR (post-consumer recycled) resin.

Crescent H (Halal)

Product Details

UPC / SKU 7 33739 03373 4

DSLD Entry Date 2025-09-25

Product Type Other Combinations

Form Capsule

Brand NOW Solutions

DSLD ID 335332

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →