Is 12.5 mcg of Vitamin D safe?

Yes — this is 0.8× the recommended daily intake of 0.015 mg, which is within safe limits.

Is 34 mg of Vitamin E safe?

Yes — this is 2.3× the recommended daily intake of 15 mg, which is within safe limits.

Is 25 mg of Thiamine safe?

This is 20.8× the recommended daily intake of 1.2 mg. While above typical doses, it may still be within safe limits (UL: None mg).

Multi t/d by Pure Encapsulations — Ingredients, Evidence & Safety

🟢 86/100

This product is generally safe

Niacin: 37.5mg is 1.1× the Tolerable Upper Intake Level (35mg)
Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Contains proprietary blend — exact ingredient amounts not disclosed
68% of ingredients have research evidence

D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The formulation includes vitamins A, C, D, E, and thiamine, which are supported by strong evidence for maintaining immune function and cellular health. These essential nutrients play critical roles in antioxidant defense and metabolic processes. Research indicates a high safety profile for these ingredients when used within recommended daily allowances.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

⚠️ Niacin: 37.5mg is 1.1× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Capsule(s) Serving Size

120 Servings

Other Combinations Product Type

68% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

675 mg (75% DV)

Vitamin C

250 mg (278% DV)

Vitamin D

12.5 mcg (63% DV)

✅ Within RDA (0.8× RDA of 0.015 mg) 📚 608 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.0125mg UL 0.1mg

Vitamin E

34 mg (223% DV)

✅ 2.3× RDA — within safe limits 📚 179 studies (Tier A: 3, B: 90)

RDA 15mg This product: 34mg UL 1000mg

Thiamine

25 mg (2083% DV)

📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 25mg

Riboflavin

17.35 mg (1335% DV)

📊 13.3× RDA — above typical dose 📚 13 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 17.35mg

Niacin

37.5 mg (234% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 196 studies (Tier A: 5, B: 63)

RDA 14mg This product: 37.5mg UL 35mg

Vitamin B6

10.4 mg (612% DV)

📊 8.0× RDA — above typical dose (UL: 100 mg) 📚 114 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 10.4mg UL 100mg

Folate

667 mcg DFE (167% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 226 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 667mg UL 1.0mg

Vitamin B12

250 mcg (10417% DV)

📊 104.2× RDA — above typical dose 📚 139 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.25mg

Biotin

400 mcg (1333% DV)

📊 13.3× RDA — above typical dose 📚 27 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.4mg

Pantothenic Acid

25 mg (500% DV)

📊 5.0× RDA — above typical dose 📚 2 studies — no high-quality reviews

RDA 5mg This product: 25mg

Iodine

100 mcg (67% DV)

✅ Within RDA (0.7× RDA of 0.15 mg) 📚 245 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.1mg UL 1.1mg

Zinc

7.5 mg (68% DV)

✅ Within RDA (0.7× RDA of 11 mg) 📚 263 studies (Tier A: 6, B: 134)

RDA 11mg This product: 7.5mg UL 40mg

Selenium

50 mcg (91% DV)

✅ Within RDA (0.9× RDA of 0.055 mg) 📚 173 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.05mg UL 0.4mg

Chromium

100 mcg (286% DV)

✅ 2.9× RDA — within safe limits 📚 199 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.1mg

Proprietary Mixed Carotenoid Blend

212 mcg

FloraGlo

3 mg

Zeaxanthin

500 mcg

📊 Market median: 4.0mg (32 products)

This product: 0.5mg

Other Ingredients

Cellulose Water Ascorbyl Palmitate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 1 capsule, 2 times daily, with meals.

⚠️ Warnings & Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

🧪 Formulation Notes

Certified Gluten-Free by the Gluten-Free Certified Organization www.gluten.org Gluten-Free, Non-GMO & Hypoallergenic

Twice-daily multivitamin/mineral complex for daily wellness

Gluten-Free, Non-GMO & Hypoallergenic

ChromeMate brand niacin-bound chromium Zeaxanthin is sourced from OPISHARP brand.

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

GFCO.org (Gluten-Free Certification Organization) Certified Gluten-Free by the Gluten-Free Certified Organization www.gluten.org

Product Details

UPC / SKU 7 66298 01815 7

DSLD Entry Date 2023-11-22

Product Type Other Combinations

Form Capsule

Brand Pure Encapsulations

DSLD ID 299069

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →