Cogni Defend by Clean Nutraceuticals — Ingredients, Evidence & Safety

🟢 96/100

This product looks safe

Vitamin D3: 0.5mg is 5.0× the Tolerable Upper Intake Level (0.1mg)
Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
58% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin D3: 0.5mg is 5.0× the Tolerable Upper Intake Level (0.1mg)

⚠️ Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

58% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C

90 mg (100% DV)

Vitamin D3

500 mcg (2500% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 5.0× (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.5mg UL 0.1mg

Vitamin E

15 mg (100% DV)

✅ Within RDA (1.0× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 15mg UL 1000mg

Vitamin B6

2 mg (118% DV)

✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2mg UL 100mg

Folate

340 mcg DFE (85% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 340.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 340mg UL 1.0mg

Vitamin B12

100 mcg (4167% DV)

📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.1mg

Bacopa Whole Plant Extract

300 mg

Phosphatidylserine

300 mg

📊 Market median: 100.0mg (108 products)

Median 100.0mg This product: 300mg

Alpha-Glycerylphosphorylcholine

300 mg

✅ Within RDA (0.5× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 300mg UL 3500mg

Flaxseed Extract

100 mg

📊 Market median: 1000.0mg (212 products) 📚 12 studies (Tier A: 0, B: 3)

This product: 100mg

L-Theanine

100 mg

📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)

This product: 100mg

Ginkgo biloba Leaf Extract

100 mg

📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)

This product: 100mg

Cat's Claw Root Extract

50 mg

📊 Market median: 450.0mg (130 products) 📚 1 studies — no high-quality reviews

This product: 50mg

Lion's Mane Mushroom Fruiting Body Extract

50 mg

Knotweed Root Extract

50 mg

N-Acetyl Cysteine

25 mg

📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)

This product: 25mg

Uridine 5'-Monophosphate Disodium Salt

10 mg

📊 Market median: 99.0mg (503 products) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 10mg UL 4000mg

Black Pepper fruit extract

5 mg

Huperzine

400 mcg

📊 Market median: 0.15mg (41 products)

Median 0.15mg This product: 0.4mg

Other Ingredients

Bovine Gelatin Maltodextrin Silicon Dioxide Rice Flour

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement take two (2) capsules once a day. For best results take with a meal and an 8 oz glass of water or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Transparency

Made in the United States with globally sourced ingredients.

Alpha GPC, phosphatidylserine, bacopa monnieri, huperzine-a & ginkgo biloba Each serving contains: Alpha GPC 300 mg, Phosphatidylserine, Bacopa Monnieri, Huperzine-A 400 mcg, L-Theanine 100 mg & more All-in-1 Supplement

Alpha GPC Phosphati Pd dylserine Bacopa Bm Monnieri Huperzine A Extract L-Theanine Lt Ginkgo Gb Biloba Omega 3 Flax Resveratrol R Extract Lions Mane Lm Mushroom Cats Claw Cc N-Acetyl- Nc - L-Cysteine Vitamin D3 Vitamin E Vitamin C Vitamin B6 Vitamin B12