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Advanced Hair, Skin & Nails Formula

product on market Other (e.g. tea bag) GNC Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 64% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins, biotin, and zinc, which are moderately supported by research for maintaining skin and hair health. These nutrients act as essential cofactors for protein synthesis and cellular repair. However, the overall evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Advanced Hair, Skin & Nails Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Pearlized White Caplet(s)
Serving Size
30
Servings
Other Combinations
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (31% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
1 mg (59% DV)
Within RDA (0.8× RDA) 114 studies (A:3, B:35)
3000 mcg (10000% DV)
100.0× RDA — above typical dose 27 studies (A:0, B:11)
7 mg (140% DV)
1.4× RDA — within safe limits 2 studies — no high-quality reviews
3.75 mg (34% DV)
Within RDA (0.3× RDA) 263 studies (A:6, B:134)
0.5 mg (56% DV)
Within RDA (0.6× RDA) 37 studies (A:0, B:11)
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)
Red Orange fruit and peel extract
100 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
Amla Fruit Juice, Powder
12.5 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Market median: 100.0mg (173 products)
0.5 mg
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)

Other Ingredients

Cellulose Dextrose Croscarmellose Sodium Stearic Acid Magnesium Stearate Silicon Dioxide Titanium Dioxide Vanilla Flavor, Natural Mica Caramel Riboflavin Stevia leaf extract
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take contents of one packet daily with food. For maximum benefits, take as directed everyday.

Warnings & Precautions

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Keep out of reach of children.

Formulation Notes

Designed especially for women, our Women's Ultra Mega Live Well Vitapak features 100% RDA or more of 17 essential vitamins and minerals plus omega-3 fatty acids, biotin, collagen and cranberry for head-to-toe support.

Hair, skin, & nails Provides beauty support with biotin, collagen, lutein and DHA omega-3 fatty acids Eye Supports eye health with DHA omega-3 fatty acids, beta-carotene and lutein Immune support Includes vitamins C, D and B-6 plus zinc to support natural resistance Energy metabolism Combines high-potency B vitamins and magnesium for energy production

Provides women with head-to-toe nutritional support Clinically studied In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a basic vitamin formula based upon multivariate statistical analyses of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid and vitamins B-6 and B-12) and key antioxidants and carotenoids (a group of beta-carotene, alpha tocopherol, selenium, lutein and lycopene). Statistically significant improvements in SF-36 Vitality and Mental health scores were also observed compared to placebo.

Combines a clinically studied multivitamin blend, omega-3s, calcium, biotin, collagen and cranberry

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you are not satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we'll either refund your money or find you a replacement product that is right for you

No artificial flavors, no wheat, gluten free, no dairy. Gf Gluten free

Lutemax2020 Lutein & zeaxanthin Curcuwin

Additional Information

Store in a cool, dry place.

For more information: 1-888-462-2548 Shop now @ gnc.com

Metadata

Product Details

DSLD Entry Date2025-07-24
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGNC
DSLD ID331498
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.