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Thyroid Action

product on market Capsule Puritan's Pride Safety: 97/100
97/100

This product looks safe

  • Folate: 41.66mg is 41.7× the Tolerable Upper Intake Level (1.0mg)
  • 92% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains a complex of B vitamins, including thiamine, riboflavin, and niacin, which support cellular energy metabolism. There is strong evidence for the role of these nutrients in maintaining general metabolic function. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 41.66mg is 41.7× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Thyroid Action
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
75
Servings
Botanical with Nutrients
Product Type
92%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

25 mg (2083% DV)
20.8× RDA — above typical dose 76 studies (A:0, B:33)
25 mg (1923% DV)
19.2× RDA — above typical dose 13 studies (A:0, B:1)
25 mg (156% DV)
1.8× RDA — within safe limits 196 studies (A:5, B:63)
25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
41.66 mcg DFE (10% DV)
Exceeds UL by 41.7× (UL: 1.0 mg) 226 studies (A:10, B:105)
Calcium
52 mg (4% DV)
40 mg (3% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
50 mcg (91% DV)
Within RDA (0.9× RDA) 173 studies (A:0, B:67)
150 mg
Market median: 500.0mg (223 products) 24 studies (A:0, B:1)
50 mg
Market median: 1000.0mg (212 products) 12 studies (A:0, B:3)
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)

Other Ingredients

Cellulose Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one (1) capsule daily, preferably on an empty stomach.

Warnings & Precautions

Warning: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical or thyroid condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

Supports thyroid health

Additional Information

Store at room temperature.

To reorder item # 30496 www.puritan.com 1-800-645-1030

QA Quality Assured

Metadata

Product Details

UPC / SKU0 25077 00052 4
DSLD Entry Date2023-05-24
Product TypeBotanical with Nutrients
FormCapsule
BrandPuritan's Pride
DSLD ID285653
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.