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ArthroSoothe Supreme

product on market Capsule Designs for Health Safety: 98/100
98/100

This product looks safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 56% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains essential minerals and vitamins that support cellular function and antioxidant defenses. Research provides moderate evidence that zinc, selenium, and copper contribute to joint and systemic health. However, the overall evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for ArthroSoothe Supreme
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
56%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (2500% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
10 mg (67% DV)
Within RDA (0.9× RDA) 263 studies (A:6, B:134)
100 mcg (143% DV)
1.8× RDA — within safe limits 173 studies (A:0, B:67)
1 mg (50% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
1 mg (50% DV)
Within RDA (0.4× RDA) 9 studies — no high-quality reviews
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 1000.0mg (2 products)
N-Acetyl-Cysteine
200 mg
Cyplexinol(TM) PRO
100 mg
GlycoMarine(TM)
100 mg
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
75 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Cetyl Myristoleate
50 mg
Market median: 100.0mg (173 products)
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)

Other Ingredients

Microcrystalline Cellulose Vegetable Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Recommended Use: As a dietary supplement, take four capsules per day with meals, or as directed by your health care practitioner.

Warnings & Precautions

Individuals with shellsh allergies should check with their health care practitioner before taking ArthroSoothe(TM) Supreme.

Contains: Shellfish (mussels, crab, lobster, shrimp, snails, oysters).

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

Does not contain gluten.

Contains: Shellfish (mussels, crab, lobster, shrimp, snails, oysters).

Additional Information

Cyplexinol(TM) PRO PROFESSIONAL GRADE Nature's BMP - Complex

Notice: Color, size or shape may appear different between lots.

ARSSUP

For Professional Use Only

Guaranteed GMP COMPLIANT Products

Manufactured in an NSF GMP Registered Facility

STORE IN A COOL, DRY PLACE.

Metadata

Product Details

UPC / SKU879452003576
DSLD Entry Date2013-07-25
Product TypeOther Combinations
FormCapsule
BrandDesigns for Health
DSLD ID23511
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.