ArthroSoothe Supreme
98/100
This product looks safe
- Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
- 56% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
Label Data
4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
56%
Evidence Coverage
Supplement Facts — Evidence Check
500 mg
(2500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
10 mg
(67% DV)
✅ Within RDA (0.9× RDA of 11 mg)
📚 258 studies (Tier A: 6, B: 134)
100 mcg
(143% DV)
✅ 1.8× RDA — within safe limits
📚 172 studies (Tier A: 0, B: 67)
1 mg
(50% DV)
✅ 1.1× RDA — within safe limits
📚 36 studies (Tier A: 0, B: 11)
1 mg
(50% DV)
✅ Within RDA (0.4× RDA of 2.3 mg)
📚 8 studies — no high-quality reviews
1000 mg
📊 Market median: 1000.0mg (1115 products)
📚 22 studies (Tier A: 0, B: 9)
750 mg
📊 Market median: 1000.0mg (2 products)
N-Acetyl-Cysteine
200 mg
Cyplexinol(TM) PRO
100 mg
GlycoMarine(TM)
100 mg
75 mg
📊 Market median: 375.0mg (171 products)
📚 30 studies (Tier A: 1, B: 14)
75 mg
📊 Market median: 450.0mg (254 products)
📚 240 studies (Tier A: 0, B: 100)
Cetyl Myristoleate
50 mg
20 mg
📊 Market median: 100.0mg (173 products)
10 mg
📊 Market median: 167.0mg (311 products)
📚 182 studies (Tier A: 0, B: 65)
2 mg
📊 Market median: 20.0mg (931 products)
📚 233 studies (Tier A: 1, B: 90)
Other Ingredients
Microcrystalline Cellulose
Vegetable Stearate
Silicon Dioxide
Label Claims — Verification
❓
All Other
All Other (97% of products)
Structure/Function (86% of products)
Nutrient (36% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Recommended Use: As a dietary supplement, take four capsules per day with meals, or as directed by your health care practitioner.
⚠️ Warnings & Precautions
Individuals with shell sh allergies should check with their health care practitioner before taking ArthroSoothe(TM) Supreme.
Contains: Shellfish (mussels, crab, lobster, shrimp, snails, oysters).
KEEP OUT OF REACH OF CHILDREN.
🧪 Formulation Notes
Does not contain gluten.
Contains: Shellfish (mussels, crab, lobster, shrimp, snails, oysters).
Additional Information
Cyplexinol(TM) PRO PROFESSIONAL GRADE Nature's BMP - Complex
Notice: Color, size or shape may appear different between lots.
ARSSUP
For Professional Use Only
Guaranteed GMP COMPLIANT Products
Manufactured in an NSF GMP Registered Facility
STORE IN A COOL, DRY PLACE.
Product Details
UPC / SKU
879452003576
DSLD Entry Date
2013-07-25
Product Type
Other Combinations
Form
Capsule
Brand
Designs for Health
DSLD ID
23511
Data Updated
2026-04-11
Research Evidence
241
Research Sources
55
Avg Quality Score
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A
Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
A
Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
A
A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
A
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
B
Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
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