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Serotone 5HTP 50 mg

product on market Capsule Higher Nature Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

The profile includes B vitamins and zinc, which support neurotransmitter synthesis and metabolic function. Research provides strong evidence for the role of B6 and folic acid in mood regulation and cognitive health. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Serotone 5HTP 50 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

15 mg NE (94% DV)
1.1× RDA — within safe limits 196 studies (A:5, B:63)
5 mg (357% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
50 mcg (25% DV)
Within RDA (0.1× RDA) 226 studies (A:10, B:105)
25 mcg (50% DV)
Within RDA (0.8× RDA) 27 studies (A:0, B:11)
2.5 mg (25% DV)
Within RDA (0.2× RDA) 263 studies (A:6, B:134)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Rice Bran Hydroxypropyl Methylcellulose L-5-Hydroxytryptophan Niacin Zinc Citrate Pyridoxal 5-Phosphate Pyridoxine Hydrochloride Silicon Dioxide Magnesium Stearate Folic Acid Biotin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

DIRECTIONS: Adults take 1-2 capsules a day preferably before bed with a carbohydrate snack, or as your health professional advises.

Warnings & Precautions

Store in a cool, dry, steam free environment out of reach of children.

Do not exceed recommended daily intake.

WARNING: Not advisable if pregnant or taking fenfluramine. Care should also be taken if being prescribed SSRIs.

Can cause drowsiness; do not drive or operate machinery if affected. If gastro-intestinal discomfort occurs, reduce intake.

Formulation Notes

DOES NOT CONTAIN: Artificial colours, flavourings or preservatives, corn, dairy products, gluten, lactose, maize, salt, soya, sugar, wheat, yeast.

Suitable for vegetarians and vegans.

Additional Information

SE5090 109 SE5-085-02

This product is not tested on animals.

Jar {Recycle} 1 PET Lid {Recycle} 5 PP

ULTIMATE NUTRITION

- 5HTP is an amino acid needed to produce serotonin. - Vits B3 & B6 contribute to normal psychological function.

STORAGE: Store in a cool, dry, steam free environment out of reach of children.

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Metadata

Product Details

UPC / SKU5 031013 100109
DSLD Entry Date2015-01-23
Product TypeOther Combinations
FormCapsule
BrandHigher Nature
DSLD ID41869
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.